TOXICITY EFFECT OF NIGELLA SATIVA AND NIGELLA ARVENSIS SEED EXTRACT ON GASTRIC CANCER CELL LINES (AGS) AND BRAIN TUMOR CELLS (AST)

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Rashid Sheykh Ahmad Mohsen; SANJARIAN FORUOGH; SABOUNI FARZANEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Razi Journal of Medical Sciences Year:2016 | Volume:23 | Issue:148 Page(s): 72-79

Download Full-Text

Persian Verion

View:

2,162

Download:

Cites:

Information Journal Paper

Title

TOXICITY EFFECT OF NIGELLA SATIVA AND NIGELLA ARVENSIS SEED EXTRACT ON GASTRIC CANCER CELL LINES (AGS) AND BRAIN TUMOR CELLS (AST)

Author(s)

Rashid Sheykh Ahmad Mohsen | SANJARIAN FORUOGH | SABOUNI FARZANEH | Issue Writer Certificate

Keywords

NIGELLA SATIVAQ2

NIGELLA ARVENSISQ2

GASTRIC CANCERQ2

BRAIN TUMORQ2

Abstract

Background: Every year thousands of people die because of stomach cancer and BRAIN TUMORs. N. sativa plant has thymoquinone and this compound may prevent cancer cell line growth in many types of cancer. The purpose of this study was to examine the possibility of inhibiting cell growth in human stomach gastric adenocarcinoma (AGS) and astrocytoma cell lines (AST) by N. sativa and N. arvensis extract and to compare lethal effect of these two extracts on cancer cell line.Methods: AGS and AST cell lines were cultured and seeded for 7 hours. After this time these cells treated with various concentration of N. sativa and N. arvensis extracts for 24 hours. Consequently, the cytotoxicity effect of extract on cell line was investigated by MTT (3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide) assay.Results: Based on our data the extract of N. sativa has cytotoxic effects on both AGS and AST cell lines. Although in case of astrocytoma cell line this effect is not dose dependent, in AGS cell line the results do not follow the same pattern and at lower three doses the cytotoxicity effect was dose dependent. The cytotoxicity effect of N. arvensis extract on astrocytoma cell line was dose independent, but in AGS cell line this effect was dose dependent.Conclusion: According to the results of this study extracts of both N. sativa and N. arvensis showed cytotoxicity effect on examined cancer cell lines.

Cites

No record.

References

REVIEW OF PREVENTIVE AND THERAPEUTIC EFFECTS OF CURCUMIN IN PATIENTS WITH CANCER

Cite

APA: Copy

Rashid Sheykh Ahmad, Mohsen, SANJARIAN, FORUOGH, & SABOUNI, FARZANEH. (2016). TOXICITY EFFECT OF NIGELLA SATIVA AND NIGELLA ARVENSIS SEED EXTRACT ON GASTRIC CANCER CELL LINES (AGS) AND BRAIN TUMOR CELLS (AST). RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 23(148), 72-79. SID. https://sid.ir/paper/10209/en

Vancouver: Copy

Rashid Sheykh Ahmad Mohsen, SANJARIAN FORUOGH, SABOUNI FARZANEH. TOXICITY EFFECT OF NIGELLA SATIVA AND NIGELLA ARVENSIS SEED EXTRACT ON GASTRIC CANCER CELL LINES (AGS) AND BRAIN TUMOR CELLS (AST). RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2016;23(148):72-79. Available from: https://sid.ir/paper/10209/en

IEEE: Copy

Mohsen Rashid Sheykh Ahmad, FORUOGH SANJARIAN, and FARZANEH SABOUNI, “TOXICITY EFFECT OF NIGELLA SATIVA AND NIGELLA ARVENSIS SEED EXTRACT ON GASTRIC CANCER CELL LINES (AGS) AND BRAIN TUMOR CELLS (AST),” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 23, no. 148, pp. 72–79, 2016, [Online]. Available: https://sid.ir/paper/10209/en

Related Journal Papers