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Information Journal Paper

Title

Effect of eight weeks of high-intensity intermittent training (HIIT) and low-intensity endurance training (LIET) with a high-fat diet on the expression of PPARα,and PLIN5 of skeletal tissue in overweight male rats

Pages

  407-415

Abstract

 Background: Obesity is a metabolic disorder in which proteins involved in fat metabolism are altered. Because obesity is a growing disease among people living in today's societies, the purpose of this study was to compare the effects of 8 weeks of high-intensity intermittent training and low-intensity endurance training on PPARα,and PLIN5 gene expression in skeletal muscle of overweight rats. Materials and Methods: Forty male Wistar rats, 5 weeks old, weighing 148. 4 ±, 22. 8 g were randomly divided into four equal groups (n=10): control, LIET, HIIT which fed high fat diet, and sham group which fed standard diet. Forty-eight hours after the end of the training program (eight weeks of intense intermittent exercise or HIIT and continued Low-intensity exercise or (LIET) the rat adipose tissue was isolated under sterile conditions. Finally, expression levels of PPARα,and PLIN5 of skeletal tissue were measured by the Real-time PCR method. Results: The data indicated that the expression level of the PPARα,and PLIN5 was significantly increased in HIIT and LIET groups compared to the control group (P= 0. 001). Conclusion: HIIT and LIET exercises increased the expression of the PLINS gene in skeletal muscle by increasing the expression of the PPARα,gene in lipid droplets of skeletal muscle.

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    APA: Copy

    SADEGHI, S., & TAGHIAN, F.. (2022). Effect of eight weeks of high-intensity intermittent training (HIIT) and low-intensity endurance training (LIET) with a high-fat diet on the expression of PPARα,and PLIN5 of skeletal tissue in overweight male rats. FEYZ, 26(4 ), 407-415. SID. https://sid.ir/paper/1022831/en

    Vancouver: Copy

    SADEGHI S., TAGHIAN F.. Effect of eight weeks of high-intensity intermittent training (HIIT) and low-intensity endurance training (LIET) with a high-fat diet on the expression of PPARα,and PLIN5 of skeletal tissue in overweight male rats. FEYZ[Internet]. 2022;26(4 ):407-415. Available from: https://sid.ir/paper/1022831/en

    IEEE: Copy

    S. SADEGHI, and F. TAGHIAN, “Effect of eight weeks of high-intensity intermittent training (HIIT) and low-intensity endurance training (LIET) with a high-fat diet on the expression of PPARα,and PLIN5 of skeletal tissue in overweight male rats,” FEYZ, vol. 26, no. 4 , pp. 407–415, 2022, [Online]. Available: https://sid.ir/paper/1022831/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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