SURVIVAL ANALYSIS OF ACUTE MYELOID LEUKEMIA

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SAFFAR AZAM; RAHGOZAR MEHDI; SHAHI FARHAD; BIGLARIAN AKBAR

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Journal: Razi Journal of Medical Sciences Year:2015 | Volume:22 | Issue:134 Page(s): 41-48

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Information Journal Paper

Title

SURVIVAL ANALYSIS OF ACUTE MYELOID LEUKEMIA

Author(s)

SAFFAR AZAM | RAHGOZAR MEHDI | SHAHI FARHAD | BIGLARIAN AKBAR | Issue Writer Certificate

Keywords

SURVIVAL ANALYSISQ2

COX MODELQ2

ACUTE MYELOIDQ2

Abstract

Background: Blood cancer (leukemia) is the cancer of blood tissue and ACUTE MYELOID Leukemia (AML) is the third most prevalent type in Iran. Survival time after diagnosis and its risk factors are one of the most important indicators for assessing the treatment.Methods: Data for this prospective study belong to Valiasr 2 (Imam Khomeini Hospital) AML patients during 2008-2013. A total of 85 patients were enrolled and death time was considered as failure event for them. Kaplan-Meier method and Cox proportional hazard model were used to identify the risk factors of patient’s survival. The SPSS v.21 and SAS v. 9.2 were used for analysis of data and a=0.05 was considered as significant level.Results: Of 85 patients, 46 (54.1%) were male. The mean age at diagnosis time was 41.38 yr., and median survival time was 17.27, and 53 patients died. Age at diagnosis, marital status, smoking, bone marrow transplants, disease history, region, lodging and resistance to treatment, and some laboratory factors (such as the number of white blood cells and red blood cells, mean corpuscular hemoglobin, sodium, potassium and calcium) were significant on survival time of patients.Conclusion: Because of the importance of leukemia, especially the role of AML type in mortality, an emphasis on age at diagnosis, marital status, smoking, bone marrow transplant, disease history, region and resistance to treatment and some laboratory factors are very important in the prognosis of death in patients.

Cites

SURVIVAL ANALYSIS OF BREAST CANCER DATA USING NONHOMOGENEOUS MULTI-STATE MODEL

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APA: Copy

SAFFAR, AZAM, RAHGOZAR, MEHDI, SHAHI, FARHAD, & BIGLARIAN, AKBAR. (2015). SURVIVAL ANALYSIS OF ACUTE MYELOID LEUKEMIA. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 22(134), 41-48. SID. https://sid.ir/paper/10274/en

Vancouver: Copy

SAFFAR AZAM, RAHGOZAR MEHDI, SHAHI FARHAD, BIGLARIAN AKBAR. SURVIVAL ANALYSIS OF ACUTE MYELOID LEUKEMIA. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2015;22(134):41-48. Available from: https://sid.ir/paper/10274/en

IEEE: Copy

AZAM SAFFAR, MEHDI RAHGOZAR, FARHAD SHAHI, and AKBAR BIGLARIAN, “SURVIVAL ANALYSIS OF ACUTE MYELOID LEUKEMIA,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 22, no. 134, pp. 41–48, 2015, [Online]. Available: https://sid.ir/paper/10274/en

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