ANTICANCER EFFECTS OF SAFFRON STIGMA (CROCUS SATIVUS): A REVIEW STUDY

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HOSHYAR REYHANE; MOSTAFAVINIA SEYEDEH ELHAM; BATHAIE SEYEDEH ZAHRA

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Paper Information

Journal: Razi Journal of Medical Sciences Year:2016 | Volume:22 | Issue:140 Page(s): 69-78

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Title

ANTICANCER EFFECTS OF SAFFRON STIGMA (CROCUS SATIVUS): A REVIEW STUDY

Author(s)

HOSHYAR REYHANE | MOSTAFAVINIA SEYEDEH ELHAM | BATHAIE SEYEDEH ZAHRA | Issue Writer Certificate

Keywords

SAFFRON STIGMAQ2

CANCERQ2

IN VITROQ2

IN VIVOQ2

Abstract

Background: Nowadays one of the most common causes of death is CANCER worldwide, which its incidence and mortality rate dramatically increasing in Iran. Saffron herb is locally grown in South Khorasan. The present study reviewed the anticancer properties of SAFFRON STIGMA on various macromolecule, cell, and animal models. In traditional medicine saffron herb treated many diseases including diabetes, blood pressure and CANCER. The modern medical findings indicate that this herb and its active metabolites can be used to produce alternative antitumor drugs. Saffron selectively suppressed growth and proliferation of CANCER cells while did not show any inhibitory effect on growth of normal cells. In addition, it reduced the side effects of common therapies. The main components of SAFFRON STIGMA are monoterpene aldehydes and carotenoides. Its carotenoids, for instance crocin and crocetin, illustrated antioxidant, anticancer and antimutagenic properties more than other metabolites.This review suggested that anti-tumor drugs from SAFFRON STIGMA can be applied as alternative, safe and promising agents.

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APA: Copy

HOSHYAR, REYHANE, MOSTAFAVINIA, SEYEDEH ELHAM, & BATHAIE, SEYEDEH ZAHRA. (2016). ANTICANCER EFFECTS OF SAFFRON STIGMA (CROCUS SATIVUS): A REVIEW STUDY. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 22(140), 69-78. SID. https://sid.ir/paper/10541/en

Vancouver: Copy

HOSHYAR REYHANE, MOSTAFAVINIA SEYEDEH ELHAM, BATHAIE SEYEDEH ZAHRA. ANTICANCER EFFECTS OF SAFFRON STIGMA (CROCUS SATIVUS): A REVIEW STUDY. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2016;22(140):69-78. Available from: https://sid.ir/paper/10541/en

IEEE: Copy

REYHANE HOSHYAR, SEYEDEH ELHAM MOSTAFAVINIA, and SEYEDEH ZAHRA BATHAIE, “ANTICANCER EFFECTS OF SAFFRON STIGMA (CROCUS SATIVUS): A REVIEW STUDY,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 22, no. 140, pp. 69–78, 2016, [Online]. Available: https://sid.ir/paper/10541/en

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