POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS

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MOOSSAVI ABDOLLAH; FARAJI LEILA

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Journal: Razi Journal of Medical Sciences Year:2016 | Volume:22 | Issue:140 Page(s): 43-54

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Title

POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS

Author(s)

MOOSSAVI ABDOLLAH | FARAJI LEILA | Issue Writer Certificate

Keywords

TINNITUSQ3

SYNAPTIC PLASTICITYQ2

DORSAL COCHLEAR NUCLEUS (DCN)Q2

Abstract

Background: TINNITUS is a specific auditory sensitivity in which the patient hears nonexistent sounds. From neurological point of view, in majority of them increment in neural activity has been characterized by increase in spontaneous firing rate in central auditory system.According to a hypothesis, TINNITUS is a result of abnormal SYNAPTIC PLASTICITY and reduced inhibitory amino acidic NTM in auditory neural network. This compensatory reduction of inhibition to partial differentiation (due to hearing pathologies, acoustic trauma, …) results in elevated neural firing rate and hyperactivity mainly in fusiform cells in DCN. In this review article was Effort survey effect of DCN SYNAPTIC PLASTICITY and TINNITUS.Methods: At this review article, some articles about SYNAPTIC PLASTICITY and TINNITUS in DCN from Google scholar, PubMed and Scopus and Science Direct were searched from 1988 to 2013 and reviewed accordingly.Results: DCN is the lowest level of auditory system and SYNAPTIC PLASTICITY and hyperactivity after hearing impairment occur there. This event increases the tendency to TINNITUS. Though, this does not mean other auditory centers have no effect in TINNITUS.

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APA: Copy

MOOSSAVI, ABDOLLAH, & FARAJI, LEILA. (2016). POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 22(140), 43-54. SID. https://sid.ir/paper/10544/en

Vancouver: Copy

MOOSSAVI ABDOLLAH, FARAJI LEILA. POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2016;22(140):43-54. Available from: https://sid.ir/paper/10544/en

IEEE: Copy

ABDOLLAH MOOSSAVI, and LEILA FARAJI, “POSSIBLE ROLE OF SYNAPTIC PLASTICITY IN DCN, AS FACTOR FOR SUBJECTIVE TINNITUS,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 22, no. 140, pp. 43–54, 2016, [Online]. Available: https://sid.ir/paper/10544/en

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