A COMPARATIVE STUDY ON THE SEDATIVE EFFECT OF ORAL KETAMINE AND PROMETHAZINE AS PREANESTHETIC MEDICATION IN OUT-PATIENT PEDIATRIC SURGERY

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TARIGH S.A.; PAYDAR A.R.; KHOSRAVI A.

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Journal: JOURNAL OF MEDICAL RESEARCH (JMR) Year:2003 | Volume:2 | Issue:1 Page(s): 7-12

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Title

A COMPARATIVE STUDY ON THE SEDATIVE EFFECT OF ORAL KETAMINE AND PROMETHAZINE AS PREANESTHETIC MEDICATION IN OUT-PATIENT PEDIATRIC SURGERY

Author(s)

TARIGH S.A. | PAYDAR A.R. | KHOSRAVI A. | Issue Writer Certificate

Keywords

ANXIETYQ2

CHILDRENQ3

SEDATIONQ3

SURGERYQ3

KETAMINEQ3

PROMETHAZINEQ3

Abstract

Background: SURGERY is usually accompanied by ANXIETY and apprehension. This, in particular, is obvious in CHILDREN during separation from their parents and entry to the operating room. A variety of drugs and techniques, such as parenteral or oral medication and preanesthesia visits have been advocated in order to prevent or to minimize this problem. This study evaluated the sedative efficacy of KETAMINE and PROMETHAZINE in CHILDREN before an operation. Patients and Methods: One hundred patients with an age range of 2 to 10 years and in class I or II according to the American Society of Anesthesiologists, who had been referred as out-patients for elective SURGERY of the extremities and lower abdomen were enrolled in this study. The patients were randomly divided into two groups of 50 patients; one group received KETAMINE 10 milligrams per kilogram diluted in 5% dextrose water and the other group received PROMETHAZINE 4 milligrams per kilogram orally one hour before operation. The patients were evaluated on the basis of their response to separation from parents and tolerance to intravenous cannulation. Results: The esults demonstrated that the response in the KETAMINE group was mild in 72%, moderate in 20% and severe in 8%, whereas the response in the PROMETHAZINE group was 44%, 40% and 16%, respectively. Conclusion: Both KETAMINE and PROMETHAZINE seem to be effective as oral premedicants for SEDATION before SURGERY in CHILDREN, although orally administered KETAMINE was more effective than PROMETHAZINE (p<0.05).

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APA: Copy

TARIGH, S.A., PAYDAR, A.R., & KHOSRAVI, A.. (2003). A COMPARATIVE STUDY ON THE SEDATIVE EFFECT OF ORAL KETAMINE AND PROMETHAZINE AS PREANESTHETIC MEDICATION IN OUT-PATIENT PEDIATRIC SURGERY. JOURNAL OF MEDICAL RESEARCH (JMR), 2(1), 7-12. SID. https://sid.ir/paper/105783/en

Vancouver: Copy

TARIGH S.A., PAYDAR A.R., KHOSRAVI A.. A COMPARATIVE STUDY ON THE SEDATIVE EFFECT OF ORAL KETAMINE AND PROMETHAZINE AS PREANESTHETIC MEDICATION IN OUT-PATIENT PEDIATRIC SURGERY. JOURNAL OF MEDICAL RESEARCH (JMR)[Internet]. 2003;2(1):7-12. Available from: https://sid.ir/paper/105783/en

IEEE: Copy

S.A. TARIGH, A.R. PAYDAR, and A. KHOSRAVI, “A COMPARATIVE STUDY ON THE SEDATIVE EFFECT OF ORAL KETAMINE AND PROMETHAZINE AS PREANESTHETIC MEDICATION IN OUT-PATIENT PEDIATRIC SURGERY,” JOURNAL OF MEDICAL RESEARCH (JMR), vol. 2, no. 1, pp. 7–12, 2003, [Online]. Available: https://sid.ir/paper/105783/en

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