THE EFFECT OF EGG YOLK AND GUM TRAGACUNT OINTMENT ON WOUND HEALING :AN EXPERIMENTAL STUDY ON RABBITS

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HOJATI H.; KAZEMI KOROUSH; TANIDEH N.; SYVANI E.; ROUSHAN N.

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Journal: JOURNAL OF MEDICAL RESEARCH (JMR) Year:2004 | Volume:2 | Issue:2 Page(s): 33-39

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Title

THE EFFECT OF EGG YOLK AND GUM TRAGACUNT OINTMENT ON WOUND HEALING :AN EXPERIMENTAL STUDY ON RABBITS

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Keywords

WOUND HEALINGQ3

TOPICAL OINTMENTQ4

EPIDERMAL GROWTH FACTORQ4

Abstract

Background: Management of wounds is still a major problem in medicine. Acceleration in the rate of WOUND HEALING, especially in diabetics, ischemic and burn patients, may reduce the costs as well as duration of hospital stay. Different topical agents have been used for WOUND HEALING. In this study, the effect of an experimental ointment on WOUND HEALING has been studied on rabbits. Materials and Methods: Twenty white rabbits were equally divided in groups A and B. The ointment was made by an equal amount of egg yolk and gum tragacunt in the laboratory. On the back of the animal (interscapular area) a 3x3 cm deep full thickness wound was induced. For the first 3 days, only irrigation by normal saline and dressing was done. From the 4th day the wounds were separately managed in each group. In group A, 25 grams of the ointment was applied daily and in group B only irrigation with normal saline and tie-over dressing was performed daily. WOUND HEALING was assessed by measuring the size and the wound was allowed to heal by secondary WOUND HEALING. No oral or topical antibiotics were used. Results: At the end of the second week, 8 cases (80%) in group A had a 1x1 cm wound and 2 cases (20%) had a 2x2 cm wound. In group B (control), 7 cases (70%) had a 2x2 cm wound, 2 cases (20%) had a 1x1 cm wound and one case had a 1.5x1.5 cm wound. Two cases in group B and one case in group A developed clinical wound infection that was managed. At the end of the study (5th week), in group A, complete healing of the wounds was observed in 7 cases (70%) without any scar formation and the incision lines were difficult to find and in 2 cases (20%) the size of the wound was 0.5x0.5 cm. In group B, 8 cases (80%) had a 1.5x1.5 cm wound and complete WOUND HEALING (less than 0.5x0.5 cm) was seen in 2 cases (20%). Conclusion: From the results of this study, it can be concluded that this mixture may contain some growth factors which can induce epithelialization and promote WOUND HEALING.

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APA: Copy

HOJATI, H., KAZEMI, KOROUSH, TANIDEH, N., SYVANI, E., & ROUSHAN, N.. (2004). THE EFFECT OF EGG YOLK AND GUM TRAGACUNT OINTMENT ON WOUND HEALING :AN EXPERIMENTAL STUDY ON RABBITS. JOURNAL OF MEDICAL RESEARCH (JMR), 2(2), 33-39. SID. https://sid.ir/paper/105796/en

Vancouver: Copy

HOJATI H., KAZEMI KOROUSH, TANIDEH N., SYVANI E., ROUSHAN N.. THE EFFECT OF EGG YOLK AND GUM TRAGACUNT OINTMENT ON WOUND HEALING :AN EXPERIMENTAL STUDY ON RABBITS. JOURNAL OF MEDICAL RESEARCH (JMR)[Internet]. 2004;2(2):33-39. Available from: https://sid.ir/paper/105796/en

IEEE: Copy

H. HOJATI, KOROUSH KAZEMI, N. TANIDEH, E. SYVANI, and N. ROUSHAN, “THE EFFECT OF EGG YOLK AND GUM TRAGACUNT OINTMENT ON WOUND HEALING :AN EXPERIMENTAL STUDY ON RABBITS,” JOURNAL OF MEDICAL RESEARCH (JMR), vol. 2, no. 2, pp. 33–39, 2004, [Online]. Available: https://sid.ir/paper/105796/en

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