HEPATITIS B

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FATAHI M.R.; KESHAVARZ R.

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Journal: JOURNAL OF MEDICAL RESEARCH (JMR) Year:2004 | Volume:2 | Issue:3 Page(s): 27-32

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Information Journal Paper

Title

HEPATITIS B "E" ANTIGEN (HBEAG) STATUS AND ITS RELATION TO TRANSAMINASE LEVEL IN PATIENTS CHRONICALLY INFECTED WITH HEPATITIS B SURFACE ANTIGEN (HBSAG) IN SOUTHWESTERN IRAN (1999-2001)

Author(s)

FATAHI M.R. | KESHAVARZ R. | Issue Writer Certificate

Keywords

HBEAGQ4

HBEABQ4

HEPATITIS BQ3

ALTQ4

CHRONIC HEPATITISQ3

Abstract

Background: There is a wide variation in the frequency of HBEAG among HBsAg infected patients in the world with possible prognostic significance. Patients and Methods: In this prospective study, three-hundred and seven patients who were found to be HBsAg positive either during a blood donation or incidentally in a routine check-up, were evaluated by testing HBEAG, HBEAB, serum alanine transaminase (ALT) and serum alfa-fetoprotein. Liver ultrasound was performed in all patients. Patients were then divided into two groups: Group A (HBEAG positive) and Group B (HBEAG negative). The correlation of this viral marker (HBEAG) with a necroinflammatory index (ALT) was evaluated. Results: HBEAG was positive in 50 cases (16.3%) and its antibody (HBeAb) was detected in the remaining 257 patients (83.7%). Serum ALT was abnormal (>2.5 times the normal level) in 16 (32%) of HBEAG positive and 39 (15) of HBEAG negative cases. Among 55 patients with an increase in ALT, 16 (29%) cases were positive for HBEAG while 39 (71%) patients were HBEAG negative. The rate of HBEAG in patients with a normal enzyme level was 13.5% (34 out of 252). Conclusion: The rate of HBEAG negativity among chronic HBsAg infected patients in our area (southwestern Iran) is in the range reported from other parts of the world. Additionally, HBEAG has a positive correlation with the level of ALT.

Cites

THE CORRELATION BETWEEN HBE-AG AND ALANINE AMINOTRANSFERASE LEVELS IN CHRONIC HEPATITIS B WITH PCR POSITIVE PATIENTS

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APA: Copy

FATAHI, M.R., & KESHAVARZ, R.. (2004). HEPATITIS B "E" ANTIGEN (HBEAG) STATUS AND ITS RELATION TO TRANSAMINASE LEVEL IN PATIENTS CHRONICALLY INFECTED WITH HEPATITIS B SURFACE ANTIGEN (HBSAG) IN SOUTHWESTERN IRAN (1999-2001). JOURNAL OF MEDICAL RESEARCH (JMR), 2(3), 27-32. SID. https://sid.ir/paper/105803/en

Vancouver: Copy

FATAHI M.R., KESHAVARZ R.. HEPATITIS B "E" ANTIGEN (HBEAG) STATUS AND ITS RELATION TO TRANSAMINASE LEVEL IN PATIENTS CHRONICALLY INFECTED WITH HEPATITIS B SURFACE ANTIGEN (HBSAG) IN SOUTHWESTERN IRAN (1999-2001). JOURNAL OF MEDICAL RESEARCH (JMR)[Internet]. 2004;2(3):27-32. Available from: https://sid.ir/paper/105803/en

IEEE: Copy

M.R. FATAHI, and R. KESHAVARZ, “HEPATITIS B "E" ANTIGEN (HBEAG) STATUS AND ITS RELATION TO TRANSAMINASE LEVEL IN PATIENTS CHRONICALLY INFECTED WITH HEPATITIS B SURFACE ANTIGEN (HBSAG) IN SOUTHWESTERN IRAN (1999-2001),” JOURNAL OF MEDICAL RESEARCH (JMR), vol. 2, no. 3, pp. 27–32, 2004, [Online]. Available: https://sid.ir/paper/105803/en

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