Effect of Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Xerostomia: A Systematic Review and Meta-Analysis

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Katebi Katayoun; Hassanpour Shirin; ESLAMI HOSEIN; Salehnia Fatemeh; HOSSEINIFARD HOSSEIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Dentistry Year:2023 | Volume:24 | Issue:SUPPLEMENT (1) Page(s): 76-83

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Effect of Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Xerostomia: A Systematic Review and Meta-Analysis

Author(s)

Keywords

Pilocarpine

Xerostomia

Saliva

Mouthwashes

Abstract

Statement of the Problem: Xerostomia is a subjective sensation of dry mouth considered as a complex state affecting multiple oral functions. Pilocarpine may be a useful medication for the treatment of Xerostomia, but its side effects limit its use under certain conditions. Recent studies have focused on the Pilocarpine mouthwash as an alternative. Purpose: We have undertaken this study to review the latest available scientific evidence systematically, concerning the effects of Pilocarpine mouthwash on Salivary flow rate in patients with Xerostomia. Materials and Method: An electronic search for randomized controlled trials published in English until September 2021 related to Pilocarpine mouthwash and Salivary flow rate in patients with dry mouth was performed in PubMed/Medline, Web of Science, Google Schol-ar, Embase, and Scopus. A random-effects meta-analysis was conducted to evaluate the relationship between the groups. Results: Two papers with 86 patients were selected for the final review based on strict eligi-bility criteria. According to the results of the meta-analysis, the mean visual analogue scale in the patient treated with Pilocarpine mouthwash was 0. 88 unit lower than that of the control group in the fourth week follow,however, it was not statistically significant (pooled mean difference=-0. 88, 95% CI = (-2. 72,0. 95), p= 0. 34). Conclusion: It seems that the use of Pilocarpine mouthwash can increase the Salivary flow rates,however, no optimal dose and application regimen can currently be suggested due to the high heterogeneity of the data. Regarding the relief of the symptoms using Pilocarpine mouthwash, the existing evidence does not support its effectiveness.

Cites

The Effect of 1% Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Radiation-Induced Xerostomia: A Double-Blind Randomized Clinical Trial

References

Review of Oral Saliva Measurement Standard Methods

Cite

APA: Copy

Katebi, Katayoun, Hassanpour, Shirin, ESLAMI, HOSEIN, Salehnia, Fatemeh, & HOSSEINIFARD, HOSSEIN. (2023). Effect of Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Xerostomia: A Systematic Review and Meta-Analysis. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), 24(SUPPLEMENT (1)), 76-83. SID. https://sid.ir/paper/1075458/en

Vancouver: Copy

Katebi Katayoun, Hassanpour Shirin, ESLAMI HOSEIN, Salehnia Fatemeh, HOSSEINIFARD HOSSEIN. Effect of Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Xerostomia: A Systematic Review and Meta-Analysis. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2023;24(SUPPLEMENT (1)):76-83. Available from: https://sid.ir/paper/1075458/en

IEEE: Copy

Katayoun Katebi, Shirin Hassanpour, HOSEIN ESLAMI, Fatemeh Salehnia, and HOSSEIN HOSSEINIFARD, “Effect of Pilocarpine Mouthwash on Salivary Flow Rate in Patients with Xerostomia: A Systematic Review and Meta-Analysis,” JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), vol. 24, no. SUPPLEMENT (1), pp. 76–83, 2023, [Online]. Available: https://sid.ir/paper/1075458/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops