COMPARISON OF SERUM AND PLASMA MMP-9 LEVEL IN BREAST CANCER PATIENTS

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SADEGHI MORTEZA; MOTEVALI BASHI MAJID

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Journal: Journal of Knowledge & Health in Basic Medical Sciences Year:2011 | Volume:6 | Issue:2 Page(s): 13-17

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Title

COMPARISON OF SERUM AND PLASMA MMP-9 LEVEL IN BREAST CANCER PATIENTS

Author(s)

SADEGHI MORTEZA | MOTEVALI BASHI MAJID | Issue Writer Certificate

Keywords

BREAST CANCERQ3

MATRIX MATALOPROTEINASE-9Q3

PLASMA LEVELQ3

SERUM LEVELQ3

Abstract

Introduction: Matrix metalloproteinase-9 (MMP-9) has recently been reported as a marker gene for several cancers. With respect to our previous results about this gene, in the present study we compare the correlation between the plasma and serum MMP-9 levels and clinical features of BREAST CANCER patients.Methods: In this case-control study, 114 BREAST CANCER patients and 87 healthy controls were studded. MMP-9 level was quantitatively measured by zymography and Bio Rad kit (Bio-Rad, Richmond, CA).Results: Plasma MMP-9 level was significantly elevated in BREAST CANCER patients compared with the control subjects (P<0.001). Also there was a correlation between the plasma MMP-9 level and lymph node metastasis (OR, 3.4, P=0.019) and venous invasion (OR, 4.14, P=0.033) of the patients. There was no correlation between the serum MMP-9 level and lymphatic metastasis or venous invasion of the patients.Conclusion: According to our findings, plasma MMP-9 level is a better marker than the serum MMP-9 level for early diagnosis of BREAST CANCER metastasis.

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APA: Copy

SADEGHI, MORTEZA, & MOTEVALI BASHI, MAJID. (2011). COMPARISON OF SERUM AND PLASMA MMP-9 LEVEL IN BREAST CANCER PATIENTS. KNOWLEDGE AND HEALTH, 6(2), 13-17. SID. https://sid.ir/paper/107925/en

Vancouver: Copy

SADEGHI MORTEZA, MOTEVALI BASHI MAJID. COMPARISON OF SERUM AND PLASMA MMP-9 LEVEL IN BREAST CANCER PATIENTS. KNOWLEDGE AND HEALTH[Internet]. 2011;6(2):13-17. Available from: https://sid.ir/paper/107925/en

IEEE: Copy

MORTEZA SADEGHI, and MAJID MOTEVALI BASHI, “COMPARISON OF SERUM AND PLASMA MMP-9 LEVEL IN BREAST CANCER PATIENTS,” KNOWLEDGE AND HEALTH, vol. 6, no. 2, pp. 13–17, 2011, [Online]. Available: https://sid.ir/paper/107925/en

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