The Effect of Topical Lidocaine Gel, Intrauterine Lidocaine Injection and Combination of these Two Methods for Relieving Pain during Curettage: A Double Blind Randomized Clinical Trial

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BEIGOM KHEZRI MARZIEH; Haji Seyed Javadi Ezzatalsadat; MOVAHED FARIDEH; ZEINALI AIDA; EMAMI ALI; Molaverdikhani Simin Dokht

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Journal Paper

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2022 | Volume:25 | Issue:2 Page(s): 25-34

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Title

The Effect of Topical Lidocaine Gel, Intrauterine Lidocaine Injection and Combination of these Two Methods for Relieving Pain during Curettage: A Double Blind Randomized Clinical Trial

Author(s)

Keywords

Curettage

Lidocaine

Pain

Abstract

Introduction Curettage is one of the most common gynecological surgeries in women. Its complication is Pain which increases dissatisfaction in patients. Therefore, it is necessary to find a way to treat this complication. This study was performed with aim to compare the effects of three methods of using Lidocaine gel in the cervix, intrauterine injection of Lidocaine, and a combination of two methods to reduce Pain during Curettage. Methods This clinical trial study was performed in 2017 on 120 patients candidates for Curettage in Qazvin Kosar Hospital. Patients were randomly divided into three groups of topical Lidocaine gel in the cervix, intrauterine injection of Lidocaine and a combination of these two methods, and the drugs were prescribed before Curettage. Vital signs and Pain were recorded in patients and other information was collected by completing the questionnaire. Data analysis was performed using statistical software (version 22) and chi-square and ANOVA tests. P<0. 05 was considered statistically significant. Results The intrauterine and intra cervical injection of Lidocaine (0. 3±, 0. 72) and then injection of intra cervical Lidocaine (0. 45±, 0. 84) alone significantly reduced Pain during Curettage in women (P=0. 04). On the other hand, no severe hemodynamic changes were observed in these patients. No complications such as nausea and vomiting and no instability of vital signs were observed in any of the groups (P>0. 05). Conclusion Intrauterine administration along with addition of topical Lidocaine gel to the cervix can be used as a simple, low-cost, and safe method as to control Pain during and after Curettage.

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APA: Copy

BEIGOM KHEZRI, MARZIEH, Haji Seyed Javadi, Ezzatalsadat, MOVAHED, FARIDEH, ZEINALI, AIDA, EMAMI, ALI, & Molaverdikhani, Simin Dokht. (2022). The Effect of Topical Lidocaine Gel, Intrauterine Lidocaine Injection and Combination of these Two Methods for Relieving Pain during Curettage: A Double Blind Randomized Clinical Trial. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 25(2 ), 25-34. SID. https://sid.ir/paper/1083063/en

Vancouver: Copy

BEIGOM KHEZRI MARZIEH, Haji Seyed Javadi Ezzatalsadat, MOVAHED FARIDEH, ZEINALI AIDA, EMAMI ALI, Molaverdikhani Simin Dokht. The Effect of Topical Lidocaine Gel, Intrauterine Lidocaine Injection and Combination of these Two Methods for Relieving Pain during Curettage: A Double Blind Randomized Clinical Trial. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2022;25(2 ):25-34. Available from: https://sid.ir/paper/1083063/en

IEEE: Copy

MARZIEH BEIGOM KHEZRI, Ezzatalsadat Haji Seyed Javadi, FARIDEH MOVAHED, AIDA ZEINALI, ALI EMAMI, and Simin Dokht Molaverdikhani, “The Effect of Topical Lidocaine Gel, Intrauterine Lidocaine Injection and Combination of these Two Methods for Relieving Pain during Curettage: A Double Blind Randomized Clinical Trial,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 25, no. 2 , pp. 25–34, 2022, [Online]. Available: https://sid.ir/paper/1083063/en

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