EVALUATION OF SERUM LEVELS OF INTERLEUKIN-6 AND -8 IN PATIENTS WITH RECURRENT APHTHOUS ULCERATIONS

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VAHEDI MOHAMMAD; ABD ELAHZADEH SH.; ABD ALSAMADI H.R.; HAJILOUEI M.; BAKIANIAN VAZIRI P.

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Journal: JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES) Year:2009 | Volume:9 | Issue:4 (21) Page(s): 332-337

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Title

EVALUATION OF SERUM LEVELS OF INTERLEUKIN-6 AND -8 IN PATIENTS WITH RECURRENT APHTHOUS ULCERATIONS

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Keywords

INTERLEUKIN-SQ2

INTERLEUKIN-6Q2

APHTHOUS ULCERSQ2

Abstract

Statement of problem: Recurrent APHTHOUS ULCERS (RAU) are one of the most common ulcers in the oral cavity.Several studies have shown conflicting variations for inflammatory cytokines and other biologic markers in recurrent APHTHOUS ULCERS.Purpose: The aim of the present study was to determine the level of IL-S and IL-6 in the serum of patients with recurrent APHTHOUS ULCERS.Materials and Method: In this case- control study, the serum levels of IL-S and lL-6 were measured in patients with recurrent APHTHOUS ULCERS (n=40) and in healthy control subjects (n=40). The cytokines levels were measured in the serum by ELISA. The data were analyzed with SPSS software using T- test.Results: The mean value of the IL-S and IL-6 in the patient group was 52.24 pg/ml and 9.39 pg/ml which were 10 and 4 times higher than that of the control group, respectively. The differences were statistically significant (p<0.01).Conclusion: The results of the present study showed that the serum levels of IL-S and lL-6 were elevated in the patient group, IL-S level being more considerable.

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APA: Copy

VAHEDI, MOHAMMAD, ABD ELAHZADEH, SH., ABD ALSAMADI, H.R., HAJILOUEI, M., & BAKIANIAN VAZIRI, P.. (2009). EVALUATION OF SERUM LEVELS OF INTERLEUKIN-6 AND -8 IN PATIENTS WITH RECURRENT APHTHOUS ULCERATIONS. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), 9(4 (21)), 332-337. SID. https://sid.ir/paper/108613/en

Vancouver: Copy

VAHEDI MOHAMMAD, ABD ELAHZADEH SH., ABD ALSAMADI H.R., HAJILOUEI M., BAKIANIAN VAZIRI P.. EVALUATION OF SERUM LEVELS OF INTERLEUKIN-6 AND -8 IN PATIENTS WITH RECURRENT APHTHOUS ULCERATIONS. JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2009;9(4 (21)):332-337. Available from: https://sid.ir/paper/108613/en

IEEE: Copy

MOHAMMAD VAHEDI, SH. ABD ELAHZADEH, H.R. ABD ALSAMADI, M. HAJILOUEI, and P. BAKIANIAN VAZIRI, “EVALUATION OF SERUM LEVELS OF INTERLEUKIN-6 AND -8 IN PATIENTS WITH RECURRENT APHTHOUS ULCERATIONS,” JOURNAL OF DENTISTRY (SHIRAZ UNIVERSITY OF MEDICAL SCIENCES), vol. 9, no. 4 (21), pp. 332–337, 2009, [Online]. Available: https://sid.ir/paper/108613/en

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