The effect of T4 thyroid hormone proliferation on U87 brain glioblastoma cells

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Pourmokhtar Boushehri Zahra; Heydari Hedieh; Sagharjoghi Farahani Morteza; GOODARZI ARASH; Badri pour Abolfazl; Hoshivar Melika

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Razi Journal of Medical Sciences Year:2018 | Volume:25 | Issue:9 Page(s): 57-65

Download Full-Text

Persian Verion

View:

604

Download:

Cites:

Information Journal Paper

Title

The effect of T4 thyroid hormone proliferation on U87 brain glioblastoma cells

Author(s)

Keywords

Thyroid Hormones T4Q2

ProliferationQ1

Glioblastoma Cells U87Q1

Abstract

Background: Considering the effect of thyroid hormone on cancer cells, as well as the development of hormonal therapies for cancer cells. The aim of this study was to investigate the effects of cytotoxic Thyroid Hormones T4 on Proliferation of brain glioblastoma cells (U87) in cell culture. Methods: In this laboratory experimental study, U87 cells were randomly divided into control group and groups exposed to doses 0. 1, 0. 5, 1, 5, 10, 20, 40, 50 Lambda (λ ) of Thyroid Hormones T4. The toxic effect of hormones was measured using MTT assay method. The data were statistically analyzed between groups using ANOVA and SPSS. Results: The results show that the survival of U87 cells at doses of 0. 5 λ of thyroid hormone T4 at 3 times of 24, 48 and 72 hours compared with other groups in different doses had the least toxic effect. Also survival of cells at 5 λ dose of thyroid hormone T4 at 24, 48 and 72 hours compared to other groups had the highest toxicity. Conclusion: Toxicity of glioblastoma cells is not dependent on thyroid hormone (T4), and results of this study showed that thyroid hormone does not affect U87 glioblastoma cells.

Cites

No record.

References

The effects of cytotoxic thyroid hormone T4 on proliferation of brain glioblastoma cells (A172) in vitro

Cite

APA: Copy

Pourmokhtar Boushehri, Zahra, Heydari, Hedieh, Sagharjoghi Farahani, Morteza, GOODARZI, ARASH, Badri pour, Abolfazl, & Hoshivar, Melika. (2018). The effect of T4 thyroid hormone proliferation on U87 brain glioblastoma cells. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 25(9 ), 57-65. SID. https://sid.ir/paper/10951/en

Vancouver: Copy

Pourmokhtar Boushehri Zahra, Heydari Hedieh, Sagharjoghi Farahani Morteza, GOODARZI ARASH, Badri pour Abolfazl, Hoshivar Melika. The effect of T4 thyroid hormone proliferation on U87 brain glioblastoma cells. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2018;25(9 ):57-65. Available from: https://sid.ir/paper/10951/en

IEEE: Copy

Zahra Pourmokhtar Boushehri, Hedieh Heydari, Morteza Sagharjoghi Farahani, ARASH GOODARZI, Abolfazl Badri pour, and Melika Hoshivar, “The effect of T4 thyroid hormone proliferation on U87 brain glioblastoma cells,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 25, no. 9 , pp. 57–65, 2018, [Online]. Available: https://sid.ir/paper/10951/en

Related Journal Papers