Familial Fibroadenoma of Breast: A Case Series of Uncommon Presentation of a Common Disease

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Koshariya Mahim; Khare Vidhu S.; Patel Badri; Shukla Shikha; Gupta Aryesh K.; Riyaz Mohammad; Kumar Gyanendra

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Journal Paper

Paper Information

Journal: Archives of Breast Cancer Year:2022 | Volume:9 | Issue:2 Page(s): 236-239

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Information Journal Paper

Title

Familial Fibroadenoma of Breast: A Case Series of Uncommon Presentation of a Common Disease

Author(s)

Keywords

Fibroadenoma

Multiple

Bilateral

Familial

Abstract

Background: Fibroadenoma is the second most common tumour in the breast (after carcinoma) and is the most common tumour in women younger than 30 years. Multiple Fibroadenomas (more than five lesions in one breast) are very uncommon and are considered disease. Familial Bilateral Multiple Fibroadenoma is an exceedingly rare presentation with only one such case described earlier in medical literature where three siblings had Multiple Bilateral breast Fibroadenomas. We report a case series of Familial Fibroadenomas present in four siblings, along with one case presenting with Bilateral Multiple Fibroadenoma, which is first in the medical literature. Case Presentation: Fine needle Aspiration were suggestive of Bilateral Multiple Fibroadenoma. Upon surgery, 10 Fibroadenomas were removed from the right breast and 9 Fibroadenomas were removed from the left breast. Histopathological examination was consistent with Fibroadenoma with myxomatous change. Conclusion: Familial Fibroadenoma of the breast is an exceedingly rare presentation of a very common tumour. This was the first reported case of 4 siblings having Familial Fibroadenoma. Further studies are required to investigate the Familial nature of this disorder.

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References

Stromal MED12 exon 2 mutations in complex fibroadenomas of the breast

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APA: Copy

Koshariya, Mahim, Khare, Vidhu S., Patel, Badri, Shukla, Shikha, Gupta, Aryesh K., Riyaz, Mohammad, & Kumar, Gyanendra. (2022). Familial Fibroadenoma of Breast: A Case Series of Uncommon Presentation of a Common Disease. ARCHIVES OF BREAST CANCER, 9(2), 236-239. SID. https://sid.ir/paper/1100379/en

Vancouver: Copy

Koshariya Mahim, Khare Vidhu S., Patel Badri, Shukla Shikha, Gupta Aryesh K., Riyaz Mohammad, Kumar Gyanendra. Familial Fibroadenoma of Breast: A Case Series of Uncommon Presentation of a Common Disease. ARCHIVES OF BREAST CANCER[Internet]. 2022;9(2):236-239. Available from: https://sid.ir/paper/1100379/en

IEEE: Copy

Mahim Koshariya, Vidhu S. Khare, Badri Patel, Shikha Shukla, Aryesh K. Gupta, Mohammad Riyaz, and Gyanendra Kumar, “Familial Fibroadenoma of Breast: A Case Series of Uncommon Presentation of a Common Disease,” ARCHIVES OF BREAST CANCER, vol. 9, no. 2, pp. 236–239, 2022, [Online]. Available: https://sid.ir/paper/1100379/en

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