WITH WHICH ANESTHETIC REGIMEN, THE HEMODYNAMIC STATUS OF PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY WHILE ON β-BLOCKER USAGE, IS MORE STABLE? SUFENTANIL-CIS. ATRACURIUM OR SUFENTANIL-PANCURONIUM?

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AGHDAEI N.; FEYZ H.R.

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Journal: Razi Journal of Medical Sciences Year:2009 | Volume:15 | Issue:60-61 Page(s): 147-157

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Title

WITH WHICH ANESTHETIC REGIMEN, THE HEMODYNAMIC STATUS OF PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY WHILE ON β-BLOCKER USAGE, IS MORE STABLE? SUFENTANIL-CIS. ATRACURIUM OR SUFENTANIL-PANCURONIUM?

Author(s)

AGHDAEI N. | FEYZ H.R. | Issue Writer Certificate

Keywords

MUSCLE RELAXANTQ3

PANCURONIUMQ4

CIS-ATRACURIUMQ3

HEMODYNAMIC CHANGESQ3

CORONARY ARTERY BYPASS GRAFT (CABG)Q3

Abstract

Background and Aim: Hemodynamic stability during anesthesia and operation is the most important aim of anesthesiologists. Every anesthetic drug has its own hemodynamic effects. The interaction of these drugs with each other and with preoperative drugs of the patients may cause critical changes in patient's hemodynamic status. For a perfect anesthesia induction, while using high doses of opioids, we must add an intravenous drug such as etomidat. Selection of a MUSCLE RELAXANT, when etomidatsufentanil is used in patients taking b-blocker is very important. In the present study, we evaluated the hemodynamic effects of PANCURONIUM and CIS-ATRACURIUM in combination with a high dose of sufentanil in b-blocker using patients that are undergoing coronary artery bypass graft surgery (CABG).Patients and Methods: A prospective double blind randomized clinical trial analysis was performed on 80 patients undergoing coronary artery bypass graft surgery in Shaheed Rajaei Heart Center. Patients were divided randomly into two groups: CIS-ATRACURIUM (n=40) and PANCURONIUM (n=40).The selection of the type and dose of premedication drugs and intraoperative opioid and anesthetic in the two groups were the same. The systolic and diastolic blood pressures, mean arterial pressure, heart rate, cardiac output, cardiac index, central vein pressure and systemic vascular resistance were measured before and during induction and operation up to 60 min after induction. Results were analyzed with SPSS V. 13.0 and Repeated Measurement Analysis.Results: The multivariate analysis showed significant reduction (p>0.05) in systolic and mean arterial blood pressures in CIS-ATRACURIUM group. There was no statistically significant difference between the two comparative groups according to others indexes.Conclusion: Although CIS-ATRACURIUM reduced significantly the systolic and mean arterial blood pressures in comparison with PANCURONIUM after induction in CABG surgery of patients under treatment with b-blocker agents, there were no statistically and clinically significant changes in the heart rate and cardiac indices.

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APA: Copy

AGHDAEI, N., & FEYZ, H.R.. (2009). WITH WHICH ANESTHETIC REGIMEN, THE HEMODYNAMIC STATUS OF PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY WHILE ON β-BLOCKER USAGE, IS MORE STABLE? SUFENTANIL-CIS. ATRACURIUM OR SUFENTANIL-PANCURONIUM?. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 15(60-61), 147-157. SID. https://sid.ir/paper/11080/en

Vancouver: Copy

AGHDAEI N., FEYZ H.R.. WITH WHICH ANESTHETIC REGIMEN, THE HEMODYNAMIC STATUS OF PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY WHILE ON β-BLOCKER USAGE, IS MORE STABLE? SUFENTANIL-CIS. ATRACURIUM OR SUFENTANIL-PANCURONIUM?. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2009;15(60-61):147-157. Available from: https://sid.ir/paper/11080/en

IEEE: Copy

N. AGHDAEI, and H.R. FEYZ, “WITH WHICH ANESTHETIC REGIMEN, THE HEMODYNAMIC STATUS OF PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY WHILE ON β-BLOCKER USAGE, IS MORE STABLE? SUFENTANIL-CIS. ATRACURIUM OR SUFENTANIL-PANCURONIUM?,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 15, no. 60-61, pp. 147–157, 2009, [Online]. Available: https://sid.ir/paper/11080/en

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