FREQUENCY AND ANTIBIOTIC RESISTANCE PATTERNS IN CLINICAL STRAINS OF PSEUDOMONAS AERUGINOSA ISOLATED FROM TEHRAN HOSPITALS

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AMIRMOZAFARI NOUR; FALLAH MEHRABADI JALIL; HABIBI ALIREZA; KAZEMI DARSANKY REZA

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Journal: Razi Journal of Medical Sciences Year:2016 | Volume:23 | Issue:146 Page(s): 10-16

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Title

FREQUENCY AND ANTIBIOTIC RESISTANCE PATTERNS IN CLINICAL STRAINS OF PSEUDOMONAS AERUGINOSA ISOLATED FROM TEHRAN HOSPITALS

Author(s)

AMIRMOZAFARI NOUR | FALLAH MEHRABADI JALIL | HABIBI ALIREZA | KAZEMI DARSANKY REZA | Issue Writer Certificate

Keywords

PSEUDOMONAS AERUGINOSAQ2

NOSOCOMIAL INFECTIONSQ2

ANTIBIOTIC RESISTANTQ2

Abstract

Background: PSEUDOMONAS AERUGINOSA is an opportunistic pathogen and a major cause of NOSOCOMIAL INFECTIONS. The aim of this study was to evaluate the frequency and determine the antimicrobial resistance in clinical strains of PSEUDOMONAS AERUGINOSA isolated from Tehran hospitals in 2013.Methods: In this cross-sectional study, during six months period, 180 samples were collected from different parts of eight hospitals in Tehran using targeted sampling of the Modal Instance type. Biochemical tests were performed to identify the species and antibiotic susceptibilities by Kirby-Bauer disk diffusion protocol. The Chi-Square test was used for statistical analysis through the IBM SPSS 22 software.Results: The 159 isolates of PSEUDOMONAS AERUGINOSA (from 111 males and 48 females) were recovered from 180 clinical samples. Strains isolated from wound (%44.1) and urine (%29.8) had the highest frequency. Also, %97.5 of strains were hemolytic and only %2.5 were no nhemolytic (gamma hemolytic). Eighty eight perecent of the isolates were resistant to at least one or more antibiotic. Most resistance was observed towards cefotaxime (%62.9) and Aztreonam (%60.4). Seventy percent of the isolates were multiple drug resistance (MDR).Conclusion: In this study, PSEUDOMONAS AERUGINOSA isolates showed the lowest resistance to imipenem which is often recommended as the main antibiotic for resulted infections. The high prevalence of multi drug resistant strains is a serious warning.

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FREQUENCY AND ANTIBIOTIC RESISTANCE PATTERNS IN CLINICAL STRAINS OF PSEUDOMONAS AERUGINOSA ISOLATED FROM TEHRAN HOSPITALS

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APA: Copy

AMIRMOZAFARI, NOUR, FALLAH MEHRABADI, JALIL, HABIBI, ALIREZA, & KAZEMI DARSANKY, REZA. (2016). FREQUENCY AND ANTIBIOTIC RESISTANCE PATTERNS IN CLINICAL STRAINS OF PSEUDOMONAS AERUGINOSA ISOLATED FROM TEHRAN HOSPITALS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 23(146), 10-16. SID. https://sid.ir/paper/11112/en

Vancouver: Copy

AMIRMOZAFARI NOUR, FALLAH MEHRABADI JALIL, HABIBI ALIREZA, KAZEMI DARSANKY REZA. FREQUENCY AND ANTIBIOTIC RESISTANCE PATTERNS IN CLINICAL STRAINS OF PSEUDOMONAS AERUGINOSA ISOLATED FROM TEHRAN HOSPITALS. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2016;23(146):10-16. Available from: https://sid.ir/paper/11112/en

IEEE: Copy

NOUR AMIRMOZAFARI, JALIL FALLAH MEHRABADI, ALIREZA HABIBI, and REZA KAZEMI DARSANKY, “FREQUENCY AND ANTIBIOTIC RESISTANCE PATTERNS IN CLINICAL STRAINS OF PSEUDOMONAS AERUGINOSA ISOLATED FROM TEHRAN HOSPITALS,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 23, no. 146, pp. 10–16, 2016, [Online]. Available: https://sid.ir/paper/11112/en

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