The relationship between gene variants TGF-β 1 (rs: 1800470) with anthropometric and bone mineral density characteristics in postmenopausal women referred to Shariati Hospital in Tehran

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MORADI SAJJAD; Khorrami Leila; Maghbooli Zhila; MIRZAEI KHADIJEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Razi Journal of Medical Sciences Year:2018 | Volume:24 | Issue:164 Page(s): 43-51

Download Full-Text

Persian Verion

View:

506

Download:

Cites:

Information Journal Paper

Title

The relationship between gene variants TGF-β 1 (rs: 1800470) with anthropometric and bone mineral density characteristics in postmenopausal women referred to Shariati Hospital in Tehran

Author(s)

MORADI SAJJAD | Khorrami Leila | Maghbooli Zhila | MIRZAEI KHADIJEH | Issue Writer Certificate

Keywords

TGFβ1Q2

OsteoporosisQ1

Body compositionQ2

Postmenopausal womenQ1

Abstract

Background: Currently, genetics is considered to be a major factor in the risk of Osteoporosis and obesity. Therefore, we investigated possible association between TGFβ 1 polymorphisms (rs: 1800470) with anthropometric and bone mineral density characteristics in Postmenopausal women referred to Shariati Hospital in Tehran. Methods: In this study, 254 Postmenopausal women aged 46 to 78 years were examined. Body composition measured by Body composition Analyzer. Physical activity using the short form of physical activity questionnaire (IPAQ) was performed. Bone mineral density was measured by DEXA method. DNA samples from participants were genotyped using RFLP-PCR method. The results were analyzed by SPSS software version 20 and ANOVA method. Results: Our results showed that prevalence of Osteoporosis in lumber and hip Tehranian women were 17. 7% and 2. 4% respectively. For first time in Iran, we found that genotype frequencies for TGFβ 1 polymorphism (rs1800470) were: TT: 28. 3%, TC: 48%, CC: 23. 6% respectively. TGFβ 1 polymorphism (rs1800470) in Iranian Postmenopausal women after adjustment for age, age of menopause weight, physical activity, calorie intake were not associated with demography, Body composition and bone bharacteristics (p>0. 05). Conclusion: It seems that TGF-β 1 variants (rs: 1800470) in postmenopausal Iranian women did not have direct association with bone mineral density and Body composition.

Cites

No record.

References

No record.

Cite

Related Journal Papers