STUDY THE EFFECT OF LACTOBACILLUS BREVIS ISOLATED FROM IRANIAN TRADITIONAL CHEESE ON CUTANEOUS WOUND HEALING IN MALE RATS ON DAYS 3 AND 14

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZAHEDI FARIMA; HEYDARI NASRABADI MITRA; TAJABADI EBRAHIMI MARYAM; SHABANI MOHAMMAD; ABOUTALEBI HELIA

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Razi Journal of Medical Sciences Year:2011 | Volume:18 | Issue:88 Page(s): 16-23

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

942

Download:

Cites:

Information Journal Paper

Title

STUDY THE EFFECT OF LACTOBACILLUS BREVIS ISOLATED FROM IRANIAN TRADITIONAL CHEESE ON CUTANEOUS WOUND HEALING IN MALE RATS ON DAYS 3 AND 14

Author(s)

Keywords

CUTANEOUS WOUNDQ2

EXOPOLYSACCHARIDEQ2

HEALINGQ3

LACTOBACILLUS BREVISQ2

PROBIOTICQ2

Abstract

Background: PROBIOTICs are defined as different microorganisms that may have positive effects on preventing or treatment of special pathologic conditions. The actions of lactic acid bacteria are species and strain specific, and depend on sufficient numbers of bacteria being available in the intestines. The difficulty in identifying and classifying strains has complicated research, since benefits may only pertain to particular strains. Since there is no research regarding Iran's PROBIOTICs up to now thus, the present study was designed to investigate the effect of LACTOBACILLUS BREVIS on CUTANEOUS WOUND HEALING.Methods: In this experimental study, 22 strains of Lactobacillus isolated from dairy-traditional products of EXOPOLYSACCHARIDE production are investigated by phenol-sulfuric acid method. LACTOBACILLUS BREVIS, which had high EXOPOLYSACCHARIDE (EPS) production, was selected. A full-thickness square wound (1.5×1.5 cm) was made on the back of each rat (45 rats in 3 groups). Two groups, control and experimental were treated by eucerin and eucerin contained 1×1011 CFU/ml LACTOBACILLUS BREVIS, but the negative-control group did not receive anything. Rats were killed on days 1, 3 and 14 and wound samples were collected for histological and statistical studies. The data were expressed as mean±Standard deviation. Statistical analysis was performed with ANOVA.Results: The percent of wound HEALING (91.76%) and inflammation in experimental group on day 14 as compared to control (74.33%) and negative groups (73.51%) was significant (p<0.001). The numbers of neutrophils in experimental group were reduced in later phase of wound HEALING as compared to control and negative groups.Conclusion: The current study showed a significant reduction in inflammation and a significant acceleration in wound HEALING on the rats treated by LACTOBACILLUS BREVIS as compared to control and negative control groups. Further studies are required for detail mechanism of LACTOBACILLUS BREVIS during wound HEALING.

Cites

No record.

References

No record.

Cite

APA: Copy

ZAHEDI, FARIMA, HEYDARI NASRABADI, MITRA, TAJABADI EBRAHIMI, MARYAM, SHABANI, MOHAMMAD, & ABOUTALEBI, HELIA. (2011). STUDY THE EFFECT OF LACTOBACILLUS BREVIS ISOLATED FROM IRANIAN TRADITIONAL CHEESE ON CUTANEOUS WOUND HEALING IN MALE RATS ON DAYS 3 AND 14. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 18(88), 16-23. SID. https://sid.ir/paper/11195/en

Vancouver: Copy

ZAHEDI FARIMA, HEYDARI NASRABADI MITRA, TAJABADI EBRAHIMI MARYAM, SHABANI MOHAMMAD, ABOUTALEBI HELIA. STUDY THE EFFECT OF LACTOBACILLUS BREVIS ISOLATED FROM IRANIAN TRADITIONAL CHEESE ON CUTANEOUS WOUND HEALING IN MALE RATS ON DAYS 3 AND 14. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2011;18(88):16-23. Available from: https://sid.ir/paper/11195/en

IEEE: Copy

FARIMA ZAHEDI, MITRA HEYDARI NASRABADI, MARYAM TAJABADI EBRAHIMI, MOHAMMAD SHABANI, and HELIA ABOUTALEBI, “STUDY THE EFFECT OF LACTOBACILLUS BREVIS ISOLATED FROM IRANIAN TRADITIONAL CHEESE ON CUTANEOUS WOUND HEALING IN MALE RATS ON DAYS 3 AND 14,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 18, no. 88, pp. 16–23, 2011, [Online]. Available: https://sid.ir/paper/11195/en

Related Journal Papers