Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant?

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Solouki Amin; Manoochehrabadi Tahereh; Korani Farzaneh; Farshchi Mohammadreza

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Journal Paper

Paper Information

Journal: Caspian Journal of Internal Medicine Year:2023 | Volume:14 | Issue:3 Page(s): 586-589

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Title

Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant?

Author(s)

Solouki Amin | Manoochehrabadi Tahereh | Korani Farzaneh | Farshchi Mohammadreza | Issue Writer Certificate

Keywords

Hemoglobinopathy

Thalassemia

Hemoglobin J

Fast hemoglobin

Molecular diagnosis

Abstract

Background: Hemoglobin J is one of the Fast hemoglobin that has a more negative charge due to β, 77His→, Asp substitution. Acquisition of this hemoglobin is not associated with any specific clinical sign, but the combination of this Hemoglobinopathy with beta-Thalassemia and other hemoglobinopathies can cause challenges. Case Presentation: In this article, two cases with Hemoglobin J are introduced,the first patient for premarital testing and the other for his fatigue. The hemoglobin electrophoresis was done by Sebia capillary zone electrophoresis and Hb J as heterozygote and homozygote were determined. Conclusion: It must be noted that although this Hemoglobinopathy is not related to any problem alone but could be confusing in combination with other hemoglobinopathies or Thalassemia. In this paper, these two cases are introduced and an attempt was made to investigate the importance of molecular follow-up.

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APA: Copy

Solouki, Amin, Manoochehrabadi, Tahereh, Korani, Farzaneh, & Farshchi, Mohammadreza. (2023). Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant?. CASPIAN JOURNAL OF INTERNAL MEDICINE, 14(3), 586-589. SID. https://sid.ir/paper/1128509/en

Vancouver: Copy

Solouki Amin, Manoochehrabadi Tahereh, Korani Farzaneh, Farshchi Mohammadreza. Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant?. CASPIAN JOURNAL OF INTERNAL MEDICINE[Internet]. 2023;14(3):586-589. Available from: https://sid.ir/paper/1128509/en

IEEE: Copy

Amin Solouki, Tahereh Manoochehrabadi, Farzaneh Korani, and Mohammadreza Farshchi, “Reporting two hemoglobin J Iran cases, molecular follow-up, or is it insignificant?,” CASPIAN JOURNAL OF INTERNAL MEDICINE, vol. 14, no. 3, pp. 586–589, 2023, [Online]. Available: https://sid.ir/paper/1128509/en

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