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Information Journal Paper

Title

PaCO2-EtCO2 Gradient and D-dimer in the Diagnosis of Suspected Pulmonary Embolism

Pages

  0-0

Abstract

 Background: The diagnosis of pulmonary embolism (PE) because of nonspecific clinical presentation remains as a challenge for emergency physicians. Arterial to end‑, tidal partial pressure of carbon dioxide (P(a‑, Et)CO2 ) gradient may be useful in the evaluation of PE. This aimed to define the diagnostic role of P(a‑, Et)CO2 gradient by sidestream Capnography, as a noninvasive method, and D‑, dimer in patients with PE. Materials and Methods: Two hundred and three patients with chest pain or dyspnea who attend the hospital emergency ward were enrolled over a study period at a single academic center. PE was confirmed by multidetector computed tomography (MDCT) scans. PaCO2, EtCO2, and D‑, dimer were measured within 24 h of MDCT by capnograph. Results: The combination of P(a‑, Et)CO2 gradient (cutoff >9. 2 ng/ml) and D‑, dimer (cutoff >3011 ng/ml) with sensitivity and specificity of 30. 2% and 87. 2% showed a significant diagnostic value in detecting PE (area under the curve = 0. 577, P = 0. 045) but not alone (P > 0. 05). Conclusion: As the results show, the combination of P(a‑, Et)CO2 gradient and D‑, dimer can show an acceptable diagnostic value in detecting PE, although it suggests further research on evaluating the diagnostic value of P(a‑, Et)CO2 gradient and combining it with other diagnostic criteria to achieve a definite and generalizable result.

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    APA: Copy

    Khajebashi, Sayed Hamed, Mottaghi, Maryam, & FORGHANI, MOHSEN. (2021). PaCO2-EtCO2 Gradient and D-dimer in the Diagnosis of Suspected Pulmonary Embolism. ADVANCED BIOMEDICAL RESEARCH, 10(-), 0-0. SID. https://sid.ir/paper/1129471/en

    Vancouver: Copy

    Khajebashi Sayed Hamed, Mottaghi Maryam, FORGHANI MOHSEN. PaCO2-EtCO2 Gradient and D-dimer in the Diagnosis of Suspected Pulmonary Embolism. ADVANCED BIOMEDICAL RESEARCH[Internet]. 2021;10(-):0-0. Available from: https://sid.ir/paper/1129471/en

    IEEE: Copy

    Sayed Hamed Khajebashi, Maryam Mottaghi, and MOHSEN FORGHANI, “PaCO2-EtCO2 Gradient and D-dimer in the Diagnosis of Suspected Pulmonary Embolism,” ADVANCED BIOMEDICAL RESEARCH, vol. 10, no. -, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/1129471/en

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