The Effect of Camel Milk on Social Interaction and Repetitive Behaviors of Valproic acid-induced Autistic Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Heydari Sahar; AMIN BAHAREH; PEJHAN AKBAR; Mirmousavi Seyed Jamal; MOHAMMADZADEH MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2021 | Volume:28 | Issue:6 Page(s): 911-922

Download Full-Text

Persian Verion

View:

Download:

Cites:

Information Journal Paper

Title

The Effect of Camel Milk on Social Interaction and Repetitive Behaviors of Valproic acid-induced Autistic Rats

Author(s)

Keywords

Autism

Behavior test

Camel milk

Valproic acid

Abstract

Introduction: Autism Spectrum Disorder (ASD) is a neurodevelopmental syndrome with two main symptoms: repetitive behavior and social interaction disorder. Camel milk, due to its antioxidant, immune-modulating, antiinflammatory, and anti-apoptotic properties maybe have beneficial effects on ASD. Materials and Methods: Pregnant rats were injected intraperitoneally on day 12. 5 of gestation with 500 mg/kg Valproic acid. Then male neonatal rats were divided into five groups: Control group, Valproic acid group, camel raw milk group + risperidone, and pasteurized Camel milk group + risperidone. For the treatment period, rats have injected with risperidone (0. 2 mg/kg) three times a week, and raw and boiled Camel milk was given daily (10 ml/kg) for 42 days. Experiments of social interaction and repetitive behavior were measured at the beginning and end of the treatment period. Results: The offspring of mothers who received Valproic acid had problems in social interactions, and sociability and social preference indexes were significantly reduced. Repetitive self-glooming behaviors also increased in VPA-rats. The treatment groups improved their social and repetitive behaviors after receiving Camel milk and risperidone and were significantly different from the Valproic acid and pre-treatment groups. Moreover, sociability and social preference indexes showed an increase after treatment with Camel milk. Sociability index, social preference, social preference index, and repetitive behaviors before and after treatment between groups improved significantly (p <0. 001) after treatment. Conclusion: Treatment with a Camel milk diet improved the main behaviors of Autism symptoms, such as social interactions and repetitive movements.

Cites

No record.

References

No record.

Cite

APA: Copy

Heydari, Sahar, AMIN, BAHAREH, PEJHAN, AKBAR, Mirmousavi, Seyed Jamal, & MOHAMMADZADEH, MOHAMMAD. (2021). The Effect of Camel Milk on Social Interaction and Repetitive Behaviors of Valproic acid-induced Autistic Rats. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, 28(6 ), 911-922. SID. https://sid.ir/paper/1130286/en

Vancouver: Copy

Heydari Sahar, AMIN BAHAREH, PEJHAN AKBAR, Mirmousavi Seyed Jamal, MOHAMMADZADEH MOHAMMAD. The Effect of Camel Milk on Social Interaction and Repetitive Behaviors of Valproic acid-induced Autistic Rats. JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2021;28(6 ):911-922. Available from: https://sid.ir/paper/1130286/en

IEEE: Copy

Sahar Heydari, BAHAREH AMIN, AKBAR PEJHAN, Seyed Jamal Mirmousavi, and MOHAMMAD MOHAMMADZADEH, “The Effect of Camel Milk on Social Interaction and Repetitive Behaviors of Valproic acid-induced Autistic Rats,” JOURNAL OF SABZEVAR UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 6 , pp. 911–922, 2021, [Online]. Available: https://sid.ir/paper/1130286/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops