Introduction: Hospitals, as an important unit in the modern treatment system, using various sources, are responsible for providing, maintaining and promoting health for individuals in the community. In order to perform this important service, it is necessary to meet their needs properly. This study was conducted to design a model of factors affecting hospital services supply chain. Materials and Methods: This is a combined (qualitative-quantitative) research in which the opinions of fifteen experts about the hospital supply chain from six provinces of the country were used. After conducting a semi-structured interview, their opinions were collected until saturation and then analyzed. The framework analysis approach was used to determine the effective factors. Using Delphi method, the level of agreement of experts was evaluated. Results: After analysis and coding, finally seven main topics including financial resources, human resources, technologies, induced demand, management, supply and distribution, and construction and equipment were identified. Meanwhile, management (mean4/42±, 0/46 and mean rank5/56) was identified as the most important factor. Conclusion: Although financial or human resources and other factors inside or outside the organization affect the hospital services supply chain, but investing to improve management prevents or reduces the impact of many challenges.