THE LOCAL EFFECT OF ANTI-HYPOXIA ACTIVITY OF METHANOL EXTRACT IN VICLAHIRSUTA: AN ANALYSIS

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RAHMANPOUR ARVIN; NASIRI MEHRAN; FARAHPOUR MOHAMMADREZA

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Journal: ZANKO JOURNAL OF MEDICAL SCIENCES Year:2017 | Volume:18 | Issue:56 Page(s): 12-20

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Title

THE LOCAL EFFECT OF ANTI-HYPOXIA ACTIVITY OF METHANOL EXTRACT IN VICLAHIRSUTA: AN ANALYSIS

Author(s)

RAHMANPOUR ARVIN | NASIRI MEHRAN | FARAHPOUR MOHAMMADREZA | Issue Writer Certificate

Keywords

ANTI-HYPOXIAQ1

VICIA HIRSUTEQ1

ANTIOXIDANTSQ2

MICEQ3

Abstract

Backgrounds and Aim: Hypoxia brings about detrimental changes in the correct structureand function of the brain. Accordingly, any medication (or compound) which results in thestability and strength of the brain upon hypoxia or ischemia, would be highly remarkablemedically. ANTI-HYPOXIA compounds are effective in treatment and prevention of this problematic. Hypoxia brings significant changes to the activity of various enzymes in body, hencediscovering medical solutions which decrease the death rate seems necessary. Material and Methods: This study analyzes ANTI-HYPOXIA activity with a two-extractconcentration through three standard methods in hypoxic MICE. In this study 80 male MICE aredivided into three groups. Results: In the ANTI-HYPOXIA of blood analysis, an intraperitoneal injection through NaNO2 inthe control group, results in the death rate of 8. 013± 0. 827 during the study. Comparing to thecontrol group, both groups of Vicia hirsuta methanol extract had significant impacts(p<0. 05). In hypoxic blood circulation, the intraperitoneal injection of NaF yields significantresults. The compound was more effective at a 100 mg/kg dosage. Extract at a dose of 50mg/kg increased the survival (p<0. 05). In the hypoxic asphyxia, placing the animals in asealed glass container brings on noticeable results. At a dosage of 50 mg/kg of methanolextract of Vicia hirsuta and at a dosage of 100 mg/kg (p<0. 05) MICE were kept alive, andcomparing to the control group, these results were revealing and remarkable. Conclusion: according to the results the ANTI-HYPOXIA effects of VICIA HIRSUTE extract wasfavorable.

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APA: Copy

RAHMANPOUR, ARVIN, NASIRI, MEHRAN, & FARAHPOUR, MOHAMMADREZA. (2017). THE LOCAL EFFECT OF ANTI-HYPOXIA ACTIVITY OF METHANOL EXTRACT IN VICLAHIRSUTA: AN ANALYSIS. ZANKO JOURNAL OF MEDICAL SCIENCES, 18(56 ), 12-20. SID. https://sid.ir/paper/113070/en

Vancouver: Copy

RAHMANPOUR ARVIN, NASIRI MEHRAN, FARAHPOUR MOHAMMADREZA. THE LOCAL EFFECT OF ANTI-HYPOXIA ACTIVITY OF METHANOL EXTRACT IN VICLAHIRSUTA: AN ANALYSIS. ZANKO JOURNAL OF MEDICAL SCIENCES[Internet]. 2017;18(56 ):12-20. Available from: https://sid.ir/paper/113070/en

IEEE: Copy

ARVIN RAHMANPOUR, MEHRAN NASIRI, and MOHAMMADREZA FARAHPOUR, “THE LOCAL EFFECT OF ANTI-HYPOXIA ACTIVITY OF METHANOL EXTRACT IN VICLAHIRSUTA: AN ANALYSIS,” ZANKO JOURNAL OF MEDICAL SCIENCES, vol. 18, no. 56 , pp. 12–20, 2017, [Online]. Available: https://sid.ir/paper/113070/en

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