EFFECTS OF ABILIZOL DRUG ON BODY WEIGHT CHANGES AND KIDNEY FACTORS INADULT MALE RATS

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JAMSHIDI ALI; SHARIATI MEHRDAD; SEPEHRARA LILI; MOGHADAMNIA DAVOOD

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Journal: ZANKO JOURNAL OF MEDICAL SCIENCES Year:2018 | Volume:19 | Issue:60 Page(s): 46-57

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Title

EFFECTS OF ABILIZOL DRUG ON BODY WEIGHT CHANGES AND KIDNEY FACTORS INADULT MALE RATS

Author(s)

JAMSHIDI ALI | SHARIATI MEHRDAD | SEPEHRARA LILI | MOGHADAMNIA DAVOOD | Issue Writer Certificate

Keywords

ABILIZOLQ1

CREATININEQ2

BLOOD UREA NITROGENQ1

BODY WEIGHTQ2

ADULT MALE RATQ3

Abstract

Background and Aim: ABILIZOL is used in the treatment of schizophrenia and bipolar maniadisorders. This study aimed to find the effect of ABILIZOL on BODY WEIGHT changes and kidneyfactors in ADULT MALE RATs. Material and Method: In this experimental study, 50 ADULT MALE RATs from wistar race weredivided into five groups of 10. The control group received no drug and the sham groupreceived distilled water as the drug solvent. The experimental groups received 5, 10 and 15mg/kg of ABILIZOL drug gavage for 28 days. At the end of the experimental period, bodyweight changes were examined and blood samples were taken from all groups. CREATININE andblood urea nitrogen (BUN) were measured. Results: No significant differences were observed in BODY WEIGHT and serum levels ofcreatinine between experimental groups which received different amounts of ABILIZOL drugand the control group. The serum level of BUN in experimental groups which received10, 15mg/kg of ABILIZOL drug showed a significant reduction compared to the control group(p>0. 05). Conclusion: Results showed that ABILIZOL drug decreased BLOOD UREA NITROGEN.

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APA: Copy

JAMSHIDI, ALI, SHARIATI, MEHRDAD, SEPEHRARA, LILI, & MOGHADAMNIA, DAVOOD. (2018). EFFECTS OF ABILIZOL DRUG ON BODY WEIGHT CHANGES AND KIDNEY FACTORS INADULT MALE RATS. ZANKO JOURNAL OF MEDICAL SCIENCES, 19(60 ), 46-57. SID. https://sid.ir/paper/113121/en

Vancouver: Copy

JAMSHIDI ALI, SHARIATI MEHRDAD, SEPEHRARA LILI, MOGHADAMNIA DAVOOD. EFFECTS OF ABILIZOL DRUG ON BODY WEIGHT CHANGES AND KIDNEY FACTORS INADULT MALE RATS. ZANKO JOURNAL OF MEDICAL SCIENCES[Internet]. 2018;19(60 ):46-57. Available from: https://sid.ir/paper/113121/en

IEEE: Copy

ALI JAMSHIDI, MEHRDAD SHARIATI, LILI SEPEHRARA, and DAVOOD MOGHADAMNIA, “EFFECTS OF ABILIZOL DRUG ON BODY WEIGHT CHANGES AND KIDNEY FACTORS INADULT MALE RATS,” ZANKO JOURNAL OF MEDICAL SCIENCES, vol. 19, no. 60 , pp. 46–57, 2018, [Online]. Available: https://sid.ir/paper/113121/en

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