Effect of Combined Training along with Caffeine Supplementation on Plasma Asprosin in Middle-Aged Obese Men

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Daneshyar Saeed

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Journal Paper

Paper Information

Journal: Journal of Sabzevar University of Medical Sciences Year:2023 | Volume:30 | Issue:6 Page(s): 718-731

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Information Journal Paper

Title

Effect of Combined Training along with Caffeine Supplementation on Plasma Asprosin in Middle-Aged Obese Men

Author(s)

Daneshyar Saeed | Issue Writer Certificate

Keywords

AdipokineQ4

AsprosinQ4

CaffeineQ4

Exercise trainingQ4

ObesityQ4

Abstract

Introduction: In Obesity, the serum levels of Asprosin are pathologically upregulated, this is thus considered a therapeutic target. This study aimed to explore the effect of Exercise training as combined training (Aerobic+ Resistance training) along with Caffeine supplementation on the plasma levels of Asprosin in middle-aged obese men. Materials and Methods: 38 obese men aged 35 to 50 years, with a BMI of greater than 28 participated in the research. They were stratified randomized into 4 groups. including: 1-Control-placebo (n=10), 2-Caffeine (n=10), 3-Combined training-placebo (n=9) and 4-Caffeine and combined training (n=9). The Caffeine group consumed the Caffeine tab 4. 5 mg per kg body weight, daily, for 6 weeks. The Combined training group had concurrent aerobic and resistance training for 6 weeks (3 sessions per week). Blood samples were collected before and after the intervention, and the plasma Asprosin concentration was measured by the ELISA method. Results: By the effect of the Combined training, the Asprosin level was reduced (p=0/01). Taking Caffeine alone did not significantly reduce Asprosin (p=0/19). The Asprosin declined in the group that had both Combined training and Caffeine (p=0/01). Conclusion: In order to reduce the upregulated Asprosin in obese individuals known as pathologic, combined training is recommended and/so it is not necessary to take Caffeine along with the training.

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