Efficacy of lacosamide in the treatment of non-convulsive seizure and non-convulsive status epilepticus in septic patients: a narrative review

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Amini Kiumarth; Sahebnasagh Adeleh; MOJTAHEDZADEH MOJTABA

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Journal: Frontiers in Emergency Medicine Year:2022 | Volume:6 | Issue:3 Page(s): 0-0

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Title

Efficacy of lacosamide in the treatment of non-convulsive seizure and non-convulsive status epilepticus in septic patients: a narrative review

Author(s)

Amini Kiumarth | Sahebnasagh Adeleh | MOJTAHEDZADEH MOJTABA | Issue Writer Certificate

Keywords

Critically Ill

Intensive Care Unit

Lacosamide

Non-convulsive Seizures

Non-convulsive Status Epilepticus

Sepsis

Abstract

Non-convulsive Seizures (NCS) and Non-convulsive Status Epilepticus (NCSE) are of the acute complications of patients admitted to the Intensive Care Unit (ICU), which lead to increased mortality and morbidity. In these cases, immediate treatment with antiepileptic drugs (AEDs) is important to prevent further damage to the brain. AEDs are the first line of treatment, however, most of these medications have many side effects. In the recent years, significant advances have been made in this area and Lacosamide is one of the therapeutic options. The intravenous formulation of this drug is most popular due to the lack of drug-drug interaction and properly designed studies which have been conducted in this field. In this review, the latest findings on the effect of Lacosamide on acute non-convulsive and generalized-convulsive seizures (G-CS) are evaluated in Critically Ill patients admitted to the ICU.

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APA: Copy

Amini, Kiumarth, Sahebnasagh, Adeleh, & MOJTAHEDZADEH, MOJTABA. (2022). Efficacy of lacosamide in the treatment of non-convulsive seizure and non-convulsive status epilepticus in septic patients: a narrative review. (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE, 6(3), 0-0. SID. https://sid.ir/paper/1137227/en

Vancouver: Copy

Amini Kiumarth, Sahebnasagh Adeleh, MOJTAHEDZADEH MOJTABA. Efficacy of lacosamide in the treatment of non-convulsive seizure and non-convulsive status epilepticus in septic patients: a narrative review. (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE[Internet]. 2022;6(3):0-0. Available from: https://sid.ir/paper/1137227/en

IEEE: Copy

Kiumarth Amini, Adeleh Sahebnasagh, and MOJTABA MOJTAHEDZADEH, “Efficacy of lacosamide in the treatment of non-convulsive seizure and non-convulsive status epilepticus in septic patients: a narrative review,” (FRONTIERS IN EMERGENCY MEDICINE) ADVANCED JOURNAL OF EMERGENCY MEDICINE, vol. 6, no. 3, pp. 0–0, 2022, [Online]. Available: https://sid.ir/paper/1137227/en

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