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Title

THE EFFECTS OF MONOUNSATURATED FATTY ACID-RICH DIET ON THE SERUM LEVELS OF VISFATIN, INSULIN AND INTERLEUKIN-6 IN OVERWEIGHT WOMEN

Pages

  59-70

Abstract

 Background and Objective: Little information is available on the effects of monounsaturated fatty acidrich (MUFA-rich) diets on the serum adipocytokine levels. The objective of this study was to determine the effects of a MUFA-rich diet on the serum levels of INSULIN, VISFATIN and IL-6 in OVERWEIGHT women 25.0≥BMI≤2.9.9).Materials and Methods: This randomized cross-over clinical trial included 17 OVERWEIGHT women aged 20-50 years with a mean BMI of 27.6±2 kg/m2. The participants were randomly assigned to one of two groups consuming either a saturated fat-rich (SFA-rich; 16% SFA and 8% MUFA) or a MUFA-rich (16% MUFA and 8% SFA) diet for 6 weeks, with a 2-week washout period between the 2 periods. The percentages of energy derived from the other macronutrients were similar in the two diets. Biochemical assessments were done at the beginning and at the end of each period. Paired t-test was used for statistical analysis.Results: The mean proportions of MUFA intakes were 13% and 7% of the total energy intake for MUFA and SFA-rich diets, respectively, the corresponding values for SFA being 8.5% and 14%. The mean changes in the serum VISFATIN, INSULIN and IL-6 levels were not significantly different between the two diet periods; however, for serum VISFATIN levels, the difference (0.7±0.5 vs 0.4±0.4 nanogr/ml) was marginally significant (P=0.08). Adjustment for potential confounders did not alter these findings (P=0.1).Conclusion: The difference between the two diets as regards their effects on the serum INSULIN and adipocytokine levels did not reach statistical significanec (it was only marginal). We recommend conducting long-term interventional studies with larger sample sizes to be able to draw more definite conclusions.

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    APA: Copy

    HAGHIGHATDOOST, F., HOSSEINZADEH, M.J., KABIRI, A., & ESMAILLZADEH, A.. (2012). THE EFFECTS OF MONOUNSATURATED FATTY ACID-RICH DIET ON THE SERUM LEVELS OF VISFATIN, INSULIN AND INTERLEUKIN-6 IN OVERWEIGHT WOMEN. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, 6(4 (23)), 59-70. SID. https://sid.ir/paper/121399/en

    Vancouver: Copy

    HAGHIGHATDOOST F., HOSSEINZADEH M.J., KABIRI A., ESMAILLZADEH A.. THE EFFECTS OF MONOUNSATURATED FATTY ACID-RICH DIET ON THE SERUM LEVELS OF VISFATIN, INSULIN AND INTERLEUKIN-6 IN OVERWEIGHT WOMEN. JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY[Internet]. 2012;6(4 (23)):59-70. Available from: https://sid.ir/paper/121399/en

    IEEE: Copy

    F. HAGHIGHATDOOST, M.J. HOSSEINZADEH, A. KABIRI, and A. ESMAILLZADEH, “THE EFFECTS OF MONOUNSATURATED FATTY ACID-RICH DIET ON THE SERUM LEVELS OF VISFATIN, INSULIN AND INTERLEUKIN-6 IN OVERWEIGHT WOMEN,” JOURNAL OF NUTRITION SCIENCES & FOOD TECHNOLOGY, vol. 6, no. 4 (23), pp. 59–70, 2012, [Online]. Available: https://sid.ir/paper/121399/en

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