DESIGN AND FORMULATION OF TRAGACANTH DRESSING BANDAGE FOR BURN HEALING

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MOGHBEL A.A.H.; NAJI M.

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Paper Information

Journal: Jundishapur Scientific Medical Journal Year:2008 | Volume:7 | Issue:2 (57) Page(s): 274-283

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Title

DESIGN AND FORMULATION OF TRAGACANTH DRESSING BANDAGE FOR BURN HEALING

Author(s)

MOGHBEL A.A.H. | NAJI M. | Issue Writer Certificate

Keywords

TRAGACANTH GUMQ3

BURN DRESSINGQ3

MEDICINAL HERBSQ2

FORMULATIONQ3

VASELINE GAUZEQ3

Abstract

Objectives: The purpose of this study was to prepare an easily applicable dressing bandage of aqueous based tragacanth mucilage and compare it with vaseline oily-based gauze.Materials and Methods: Two types of 6% tragacanth mucilage, with or without 5% sodium chloride, were made. For selection an appropriate pad with a desired quality of saturated tragacanth mucilage, cotton fibers, synthetics and gauze bandages, under aseptic conditions of laminar air flow, with the same weight and ratio of (1:4) as that of VASELINE GAUZE, were prepared. In this study four animal groups (n=5) were selected. The first group left without treatment, second group VASELINE GAUZE treated (positive control group), the third and fourth groups (treatment groups) treated with saturated bandages of 6% tragacanth, with and without sodium chloride.Results: Result showed that the purchased gum was confirmed by references requirements from the viewpoint of appearance, chemical test, absence of Karaya gum and moisture amount. Examination of provided bandages showed that cotton fibers had least changes and most stability from the viewpoint of weight changes, apparent and organoleptic characteristics. The results of microbial test, confirmed the applied microbial preservatives, sterilized condition and performance accuracy of sterilization. The period of complete wound closure in treatment groups with saturated bandages of 6% tragacanth with and without salt were 12 and 13 days, respectively. Statistical comparison of these results with untreated and VASELINE GAUZE treated groups (which lasted 24 and 22 days respectively) were sifnificantly different (P<0.05). The presence or absence of salt did not have any significant effect on the pH, weight changes, appearance, organoleptic and therapeutic properties of prepared bandages of two mucilage products (P>0.05).Conclusions: In comparison with chemical products, tragacanath dressing is a natural and is a safe herbal product. Further clinical evaluations are needed to be performed on human burns.

Cites

ANTI BACTERIAL SCAFFOLDS BASED ON GUM TRAGACANTH FOR WOUND CARING UNDER MOIST CONDITIONS

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APA: Copy

MOGHBEL, A.A.H., & NAJI, M.. (2008). DESIGN AND FORMULATION OF TRAGACANTH DRESSING BANDAGE FOR BURN HEALING. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 7(2 (57)), 274-283. SID. https://sid.ir/paper/12390/en

Vancouver: Copy

MOGHBEL A.A.H., NAJI M.. DESIGN AND FORMULATION OF TRAGACANTH DRESSING BANDAGE FOR BURN HEALING. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2008;7(2 (57)):274-283. Available from: https://sid.ir/paper/12390/en

IEEE: Copy

A.A.H. MOGHBEL, and M. NAJI, “DESIGN AND FORMULATION OF TRAGACANTH DRESSING BANDAGE FOR BURN HEALING,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 7, no. 2 (57), pp. 274–283, 2008, [Online]. Available: https://sid.ir/paper/12390/en

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