DETERMINATION OF FREQUENCY DISTRIBUTION OF HLA-DR1-7 ANTIGENS IN VARIOUS FORMS OF ORAL LICHEN PLANUS WITH PCR TEST

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHALIANI PARICHEHR; JAHANSHAHI GHOLAM REZA; DORMIANI TABATABAEI FERIAL

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Isfahan Dental School Year:2011 | Volume:6 | Issue:4 Page(s): 364-370

Download Full-Text

Persian Verion

View:

1,097

Download:

Cites:

Information Journal Paper

Title

DETERMINATION OF FREQUENCY DISTRIBUTION OF HLA-DR1-7 ANTIGENS IN VARIOUS FORMS OF ORAL LICHEN PLANUS WITH PCR TEST

Author(s)

GHALIANI PARICHEHR | JAHANSHAHI GHOLAM REZA | DORMIANI TABATABAEI FERIAL | Issue Writer Certificate

Keywords

HLAQ2

ORAL LICHEN PLANUSQ3

PCRQ4

Abstract

Introduction: Lichen planus is a chronic mucocutaneous disease with unknown etiology and pathogenesis. It is thought that immunological (humoral and cellular) disorders and genetic factors, such as HLA, are involved in its pathogenesis. This study evaluated and compared frequency distribution of HLA-DR1-7 antigens in various forms of ORAL LICHEN PLANUS.Materials and methods: This retrospective case-control study was carried out on 66 lichen planus patients from May 2009 to August 2010. The subjects were evaluated in 6 groups of 11. After clinical and pathological confirmation of ORAL LICHEN PLANUS, whole blood samples were obtained for evaluation of HLA-DR1-7 presence with PCR. Data was analyzed by chi-square, t-test, and Cochran and McNemar tests (a=0.05).Results: There was a significant difference in HLA-DR2 antigen frequency, with the highest and lowest frequencies in the bullous and plaque-like forms, respectively. HLA-DR3 antigen frequency was the highest in the papular and the lowest in the reticular and bullous forms and it appeared to have a significantly higher frequency in the plaque-like form compared to the reticular and bullous forms. HLA-DR4 antigen had the highest and lowest frequencies in the erosive and papular forms, with significantly higher frequencies in the reticular and erythematous forms compared to the papular form. HLA-DR7 antigen had the highest and lowest frequencies in the plaque and bullous forms, with significantly lower frequencies in the reticular, erythematous, and popular forms compared to the plaque-like form.Conclusion: Under the limitations of the present study it was concluded that the frequency of some HLA-DR antigens were significantly different in various OLP forms. The possible effect of these antigens on the incidence of some forms of OLP necessitates further studies on the subject.

Cites

No record.

References

Cite

APA: Copy

GHALIANI, PARICHEHR, JAHANSHAHI, GHOLAM REZA, & DORMIANI TABATABAEI, FERIAL. (2011). DETERMINATION OF FREQUENCY DISTRIBUTION OF HLA-DR1-7 ANTIGENS IN VARIOUS FORMS OF ORAL LICHEN PLANUS WITH PCR TEST. JOURNAL OF ISFAHAN DENTAL SCHOOL, 6(4), 364-370. SID. https://sid.ir/paper/126119/en

Vancouver: Copy

GHALIANI PARICHEHR, JAHANSHAHI GHOLAM REZA, DORMIANI TABATABAEI FERIAL. DETERMINATION OF FREQUENCY DISTRIBUTION OF HLA-DR1-7 ANTIGENS IN VARIOUS FORMS OF ORAL LICHEN PLANUS WITH PCR TEST. JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2011;6(4):364-370. Available from: https://sid.ir/paper/126119/en

IEEE: Copy

PARICHEHR GHALIANI, GHOLAM REZA JAHANSHAHI, and FERIAL DORMIANI TABATABAEI, “DETERMINATION OF FREQUENCY DISTRIBUTION OF HLA-DR1-7 ANTIGENS IN VARIOUS FORMS OF ORAL LICHEN PLANUS WITH PCR TEST,” JOURNAL OF ISFAHAN DENTAL SCHOOL, vol. 6, no. 4, pp. 364–370, 2011, [Online]. Available: https://sid.ir/paper/126119/en

Related Journal Papers