COMPARATIVE EVALUATION OF SALIVARY IL-1α, IL-10 AND TNF-α CONCENTRATIONS IN PATIENTS WITH ORAL PEMPHIGUS VULGARIS LESIONS BY ELISA TECHNIQUE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHOZEIMEH FAEZEH; JAFARI MAJID

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Isfahan Dental School Year:2012 | Volume:7 | Issue:4 Page(s): 374-379

Download Full-Text

Persian Verion

View:

1,003

Download:

Cites:

Information Journal Paper

Title

COMPARATIVE EVALUATION OF SALIVARY IL-1α, IL-10 AND TNF-α CONCENTRATIONS IN PATIENTS WITH ORAL PEMPHIGUS VULGARIS LESIONS BY ELISA TECHNIQUE

Author(s)

KHOZEIMEH FAEZEH | JAFARI MAJID | Issue Writer Certificate

Keywords

ELISA TECHNIQUEQ3

IL-1αQ2

IL-10Q2

TNF-αQ2

PEMPHIGUS VULGARISQ2

Abstract

Introduction: Based on recent research, cytokines particularly IL-1a, IL-10, and INF-a might play a role in the pathogenesis of PEMPHIGUS VULGARIS. Some autoimmune diseases have been successfully treated with the use of antibodies against cytokines. The aim of this study was to compare salivary concentrations of IL-1a, IL-10, and TNF-a in patients with PEMPHIGUS VULGARIS and normal individuals.Materials and Methods: In this analytical-descriptive study, 24 PEMPHIGUS VULGARIS patients referring to the Department of Dermatology, Alzahra Hospital, and 26 healthy individuals were evaluated. Unstimulated salivary samples were collected by spitting method in both groups. IL-1a, IL-10, and TNF-a concentrations were measured by ELISA TECHNIQUE. The results were analyzed by t-test (a=0.05).Results: The mean salivary concentrations of IL-1a, IL-10 and TNF-a were higher in PEMPHIGUS VULGARIS patients compared to healthy subjects. The differences were significant in relation to IL-1α (p value=0.024) and TNF-a (p value=0.005) between the two groups; however, the differences were not significant in relation to IL-10 (p value=0.243).Conclusion: The increase in salivary concentrations of IL-1a and TNF-a in patients with PEMPHIGUS VULGARIS compared to healthy individuals might indicate the role of these agents in the pathogenesis of this disorder.

Cites

No record.

References

No record.

Cite

APA: Copy

KHOZEIMEH, FAEZEH, & JAFARI, MAJID. (2012). COMPARATIVE EVALUATION OF SALIVARY IL-1α, IL-10 AND TNF-α CONCENTRATIONS IN PATIENTS WITH ORAL PEMPHIGUS VULGARIS LESIONS BY ELISA TECHNIQUE. JOURNAL OF ISFAHAN DENTAL SCHOOL, 7(4), 374-379. SID. https://sid.ir/paper/126159/en

Vancouver: Copy

KHOZEIMEH FAEZEH, JAFARI MAJID. COMPARATIVE EVALUATION OF SALIVARY IL-1α, IL-10 AND TNF-α CONCENTRATIONS IN PATIENTS WITH ORAL PEMPHIGUS VULGARIS LESIONS BY ELISA TECHNIQUE. JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2012;7(4):374-379. Available from: https://sid.ir/paper/126159/en

IEEE: Copy

FAEZEH KHOZEIMEH, and MAJID JAFARI, “COMPARATIVE EVALUATION OF SALIVARY IL-1α, IL-10 AND TNF-α CONCENTRATIONS IN PATIENTS WITH ORAL PEMPHIGUS VULGARIS LESIONS BY ELISA TECHNIQUE,” JOURNAL OF ISFAHAN DENTAL SCHOOL, vol. 7, no. 4, pp. 374–379, 2012, [Online]. Available: https://sid.ir/paper/126159/en

Related Journal Papers