In Vitro Evaluation of Several Anticariogenic Agents with DifferentApplication Times on Prevention of Enamel Caries

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AHRARI FARZANEH; EBRAHIMI MASOUMEH; FORGHANI MARYAM; MEHRABKHANI MARYAM; Parisayi Iman; Jahan Tigh Malihe; Ariyan Yeganeh

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Journal: JOURNAL OF ISFAHAN DENTAL SCHOOL Year:2019 | Volume:14 | Issue:4 Page(s): 331-339

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Title

In Vitro Evaluation of Several Anticariogenic Agents with DifferentApplication Times on Prevention of Enamel Caries

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Keywords

CariesQ2

Casein phosphopeptide amorphous calcium phosphateQ3

DemineralizationQ2

EnamelQ2

HydroxyapatiteQ3

Sodium fluorideQ3

Abstract

Introduction: This study aimed to evaluate the effect of several anticariogenic agents on preventingenamel Demineralization. Materials& Methods: In this in vitro study, 60 intact premolar teeth were selected and divided mesiodistallyinto two halves to provide 120 specimens. The specimens were randomly divided into8 groups of 15 each. In groups 1 and 2, a cream containing casein phosphopeptideamorphous calcium phosphate and fluoride (MI Paste Plus), in groups 3 and 4, acream containing Hydroxyapatite and fluoride (Remin Pro), in groups 5 and 6, asodium fluoride gel (NaF) and in groups 7 and 8, artificial saliva were used. Theduration of exposure to the anticariogenic agents was 5 minutes in groups 1, 3, 5 and7, whereas in groups 2, 4, 6 and 8, the period of exposure was 30 minutes. Thisprocedure was performed daily for 4 days and the specimens were kept in distilledwater between treatments. Then, the specimens were immersed in a demineralizingsolution for 21 days. Finally, a VistaCam iX apparatus was employed to takefluorescent images from the specimens and the mineral content of the teeth wasrecorded. Data were analyzed with SPSS 20, using Kruskal-Wallis and Mann-Whitney U tests at a significance level of p value < 0. 05. Results: There were no significant differences in mineral contents of the teeth between thestudy groups at the application periods of 5 or 30 minutes (p value > 0. 05). Comparison of the mineral contents of the teeth between the two application periodsof 5 and 30 minutes indicated no significant differences in any of the study groups (pvalue > 0. 05). Conclusion: Under the conditions of this study, the effect of MI Paste Plus, Remin Pro or NaFwith the application periods of 5 or 30 minutes on preventing Enameldemineralization was similar to artificial saliva.

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APA: Copy

AHRARI, FARZANEH, EBRAHIMI, MASOUMEH, FORGHANI, MARYAM, MEHRABKHANI, MARYAM, Parisayi, Iman, Jahan Tigh, Malihe, & Ariyan, Yeganeh. (2019). In Vitro Evaluation of Several Anticariogenic Agents with DifferentApplication Times on Prevention of Enamel Caries. JOURNAL OF ISFAHAN DENTAL SCHOOL, 14(4 ), 331-339. SID. https://sid.ir/paper/126344/en

Vancouver: Copy

AHRARI FARZANEH, EBRAHIMI MASOUMEH, FORGHANI MARYAM, MEHRABKHANI MARYAM, Parisayi Iman, Jahan Tigh Malihe, Ariyan Yeganeh. In Vitro Evaluation of Several Anticariogenic Agents with DifferentApplication Times on Prevention of Enamel Caries. JOURNAL OF ISFAHAN DENTAL SCHOOL[Internet]. 2019;14(4 ):331-339. Available from: https://sid.ir/paper/126344/en

IEEE: Copy

FARZANEH AHRARI, MASOUMEH EBRAHIMI, MARYAM FORGHANI, MARYAM MEHRABKHANI, Iman Parisayi, Malihe Jahan Tigh, and Yeganeh Ariyan, “In Vitro Evaluation of Several Anticariogenic Agents with DifferentApplication Times on Prevention of Enamel Caries,” JOURNAL OF ISFAHAN DENTAL SCHOOL, vol. 14, no. 4 , pp. 331–339, 2019, [Online]. Available: https://sid.ir/paper/126344/en

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