COMPARATIVE EVALUATION OF LACTATE DEHYDROGENASE (LDH) AND ASPARTATE AMINOTRANSFERASE (AST) LEVELS IN PERIODONTAL DISEASES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AZIZI ARASH; RANJBARI ARDESHIR; GHAFARI MOHAMMAD ALI; JAHAN FATEMEH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ISFAHAN DENTAL SCHOOL Year:2011 | Volume:7 | Issue:3 Page(s): 265-271

Download Full-Text

Persian Verion

View:

1,082

Download:

Cites:

Information Journal Paper

Title

COMPARATIVE EVALUATION OF LACTATE DEHYDROGENASE (LDH) AND ASPARTATE AMINOTRANSFERASE (AST) LEVELS IN PERIODONTAL DISEASES

Author(s)

AZIZI ARASH | RANJBARI ARDESHIR | GHAFARI MOHAMMAD ALI | JAHAN FATEMEH | Issue Writer Certificate

Keywords

ASPARTATE AMINOTRANSFERASEQ2

LACTATE DEHYDROGENASEQ2

PERIODONTAL DISEASESQ2

SALIVAQ3

Abstract

Introduction: Periodontitis is a chronic multi-factorial infectious disease characterized by irreversible destruction of collagen fibers and other matrix constituents of the gingival tissues and periodontal ligament, and resorption of alveolar bone around the teeth with periodontal pocket formation. Host response to periodontal disease includes production of different enzymes that are released by stromal, epithelial or inflammatory cells associated with cell injury and cell death, including ASPARTATE AMINOTRANSFERASE and LACTATE DEHYDROGENASE. The aim of this study was to compare ASPARTATE AMINOTRANSFERASE and LACTATE DEHYDROGENASE SALIVAry levels in patients with generalized aggressive periodontitis and chronic mild-to-moderate periodontitis and healthy subjects with normal periodontium.Materials and Methods: In this experimental study, unstimulated SALIVA of 25 patients with mild-tomoderate periodontitis, 15 patients with aggressive periodontitis, and 25 subjects with healthy gingiva were collected. The mean ASPARTATE AMINOTRANSFERASE and LACTATE DEHYDROGENASE SALIVAry levels were measured by RA-ST autoanalyzer system. Data were analyzed by ANOVA and Tukey test.Results: The mean levels and standard deviations of LACTATE DEHYDROGENASE SALIVAry enzyme in generalized aggressive periodontitis, chronic mild-to-moderate periodontitis and control groups were 1713±88.4, 1492±65.4, 1108±34.5, respectively, with significant differences between the groups (p value<0.05) The mean levels and standard deviations of ASPARTATE AMINOTRANSFERASE SALIVAry enzyme in generalized aggressive periodontitis, chronic mild-to-moderate periodontitis and control groups were 55.46±5.6, 47.04±3.3 and 32.04±2.3, respectively, with significant differences (p value<0.05).Conclusion: Mean levels of ASPARTATE AMINOTRANSFERASE and LACTATE DEHYDROGENASE SALIVAry enzymes in periodontal patients were higher than those in healthy subjects and these enzymes can be good markers for determining amount of destruction of periodontal tissues.

Cites

No record.

References

No record.

Cite

Related Journal Papers