THE EFFECT OF POMEGRANATE PEEL HYDROALCOHOLIC EXTRACT AND VITAMIN E SUPPLEMENTATION ON STRENGTHENING ANTIOXIDANT DEFENSE SYSTEM IN RATS UNDER EXHAUSTIVE EXERCISE STRESS

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VEISKARAMI SAEED; FATHI NASRI MOHAMMAD HASSAN; AHMADVAND HASSAN; RASHIDI LADAN; HADIPUR MORADI FOROZAN

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Journal: Pars Journal of Medical Sciences Year:2016 | Volume:14 | Issue:4 Page(s): 34-42

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Title

THE EFFECT OF POMEGRANATE PEEL HYDROALCOHOLIC EXTRACT AND VITAMIN E SUPPLEMENTATION ON STRENGTHENING ANTIOXIDANT DEFENSE SYSTEM IN RATS UNDER EXHAUSTIVE EXERCISE STRESS

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Keywords

EXHAUSTIVE EXERCISEQ2

OXIDATIVE STRESSQ2

ANTIOXIDQ2

Abstract

Introduction: Acute EXHAUSTIVE EXERCISE increases reactive oxygen species, which may decrease ANTIOXIDant capacity of the body. Regular exercises and ANTIOXIDants consumption can improve ANTIOXIDant capacity. The present study aimed to determine the protective effect of pomegranate peel hydroalcoholic extract supplementation on oxidative responses induced by an EXHAUSTIVE EXERCISE schedule in rats. Materials and Methods: Thirty-two male rats were randomly divided into four groups of eight: control group received saline, PPHE200 group received 200 mg/kg pomegranate peel hydroalcoholic extract orally, PPHE250 gorup received 250 mg/kg pomegranate peel hydroalcoholic extract orally, and Vit E group received 5 mg/kg vitamin E orally. After eight weeks of regular EXHAUSTIVE EXERCISE the activity level of glutathione peroxidase, catalase, reduced glutathione and lipid peroxidation was measured.Results: The activity of glutathione peroxidase, catalase and reduced glutathione significantly increased in PPHE200, PPHE250 and vit E groups than in the control (p<0.05). Malondialdehyde level significantly reduced in PPHE200, PPHE250 and vitE groups than in the control (p<0.05).Conclusion: The results showed that pomegranate peel hydroalcoholic extract supplementation may be beneficial in improving ANTIOXIDant defense system and in reducing OXIDATIVE STRESS induced by an EXHAUSTIVE EXERCISE.

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References

ANTIOXIDANT EFFECT OF CINNAMON BARK EXTRACT FOLLOWING AN EXHAUSTIVE EXERCISE IN MALE RATS

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APA: Copy

VEISKARAMI, SAEED, FATHI NASRI, MOHAMMAD HASSAN, AHMADVAND, HASSAN, RASHIDI, LADAN, & HADIPUR MORADI, FOROZAN. (2016). THE EFFECT OF POMEGRANATE PEEL HYDROALCOHOLIC EXTRACT AND VITAMIN E SUPPLEMENTATION ON STRENGTHENING ANTIOXIDANT DEFENSE SYSTEM IN RATS UNDER EXHAUSTIVE EXERCISE STRESS. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 14(4), 34-42. SID. https://sid.ir/paper/130994/en

Vancouver: Copy

VEISKARAMI SAEED, FATHI NASRI MOHAMMAD HASSAN, AHMADVAND HASSAN, RASHIDI LADAN, HADIPUR MORADI FOROZAN. THE EFFECT OF POMEGRANATE PEEL HYDROALCOHOLIC EXTRACT AND VITAMIN E SUPPLEMENTATION ON STRENGTHENING ANTIOXIDANT DEFENSE SYSTEM IN RATS UNDER EXHAUSTIVE EXERCISE STRESS. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2016;14(4):34-42. Available from: https://sid.ir/paper/130994/en

IEEE: Copy

SAEED VEISKARAMI, MOHAMMAD HASSAN FATHI NASRI, HASSAN AHMADVAND, LADAN RASHIDI, and FOROZAN HADIPUR MORADI, “THE EFFECT OF POMEGRANATE PEEL HYDROALCOHOLIC EXTRACT AND VITAMIN E SUPPLEMENTATION ON STRENGTHENING ANTIOXIDANT DEFENSE SYSTEM IN RATS UNDER EXHAUSTIVE EXERCISE STRESS,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 14, no. 4, pp. 34–42, 2016, [Online]. Available: https://sid.ir/paper/130994/en

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