EFFECT OF CYPERUS ROTUNDUS RHIZOMES ON BLOOD GLUCOSE, LIPID, INSULIN AND HEPATIC ENZYMES IN INSULIN RESISTANCE MODEL OF MALE RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AHANGARPOUR A.; YAHYAVI H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Qom University of Medical Sciences Journal Year:2011 | Volume:5 | Issue:2 (18) Page(s): 70-75

Download Full-Text

Persian Verion

View:

987

Download:

Cites:

Information Journal Paper

Title

EFFECT OF CYPERUS ROTUNDUS RHIZOMES ON BLOOD GLUCOSE, LIPID, INSULIN AND HEPATIC ENZYMES IN INSULIN RESISTANCE MODEL OF MALE RATS

Author(s)

AHANGARPOUR A. | YAHYAVI H. | Issue Writer Certificate

Keywords

CYPERUSQ2

INSULINQ3

LIPIDSQ2

FRUCTOSEQ2

Abstract

Background and Objectives: Nowadays herbal medicine is excessively used in traditional medicine for diabetes. The CYPERUS rotundus rhizomes in traditional medicine are used for decreasing blood glucose and lipid. Therefore, the aim of this study was to examine the effect of rhizomes extract of this plant in INSULIN resistance model of male rats. Methods: This experimental study was carried out on 36 adult male wistar rats in the weight range of 150-200 (g). Diabetes was induced by FRUCTOSE 10% in drinking water for 8 weeks, then the animals were divided randomly into 4 groups: control, FRUCTOSE induce, aqueous extracts of CYPERUS rotundus rhizomes (500 mg/kg), MeOH extracts of CYPERUS rotundus rhizomes (500 mg/kg). 48 hours after the last gavage with extracts, the rats were fasted for 12h, then blood samples were collected from heart, serum was dissented and blood glucose, INSULIN, fasting INSULIN resistance index (FIRI), lipid profile and hepatic enzymes were determined.Results: Glucose in FRUCTOSE group in comparison with control group showed a significant increase. INSULIN in aqueous and MeOH extracts groups in comparison with control group significantly increased. FIRI in aqueous extract group in comparison with control group was significantly higher (p<0.05). Lipid profile was not change in any of them. MeOH extract, showed a decrease in all of the hepatic enzymes (Alkaline phosphatase, aspartate, and AST, alanine Transferase).Conclusion: Aqueous has could not probably be effective in decreasing diabetic complications. But is it believed that with extensive study on MeOH extracts, we can reach a more efficient decrease in diabetes and antihepatotxicity.

Cites

No record.

References

No record.

Cite

APA: Copy

AHANGARPOUR, A., & YAHYAVI, H.. (2011). EFFECT OF CYPERUS ROTUNDUS RHIZOMES ON BLOOD GLUCOSE, LIPID, INSULIN AND HEPATIC ENZYMES IN INSULIN RESISTANCE MODEL OF MALE RATS. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 5(2 (18)), 70-75. SID. https://sid.ir/paper/131994/en

Vancouver: Copy

AHANGARPOUR A., YAHYAVI H.. EFFECT OF CYPERUS ROTUNDUS RHIZOMES ON BLOOD GLUCOSE, LIPID, INSULIN AND HEPATIC ENZYMES IN INSULIN RESISTANCE MODEL OF MALE RATS. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2011;5(2 (18)):70-75. Available from: https://sid.ir/paper/131994/en

IEEE: Copy

A. AHANGARPOUR, and H. YAHYAVI, “EFFECT OF CYPERUS ROTUNDUS RHIZOMES ON BLOOD GLUCOSE, LIPID, INSULIN AND HEPATIC ENZYMES IN INSULIN RESISTANCE MODEL OF MALE RATS,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 5, no. 2 (18), pp. 70–75, 2011, [Online]. Available: https://sid.ir/paper/131994/en

Related Journal Papers