The Effect of Simultaneous Oral Consumption of Camel Milk and Urine on Cirrhosis Liver Model Induced by Carbon Tetrachloride in Male Rats

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ABABZADEH SHIMA; Sharifi Moghaddam Soroush; Eftekhari Seyed Shahin; ESLAMI FARSANI MOHSEN; Hassanzadeh Navid; MOSLEHI AZAM

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Journal: QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL Year:2019 | Volume:13 | Issue:3 Page(s): 32-39

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Title

The Effect of Simultaneous Oral Consumption of Camel Milk and Urine on Cirrhosis Liver Model Induced by Carbon Tetrachloride in Male Rats

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Keywords

CamelQ3

MilkQ1

Carbon TetrachlorideQ2

Liver cirrhosisQ1

RatQ1

Abstract

Background and Objectives: Special features of Camel urine and Milk have caused their wide consumption in Islamic and traditional medicine as an anti-microbial, antioxidant, and liver protective substance. The present study was conducted to evaluate the effect of Camel urine and Milk in Carbon Tetrachloride (CCL4) induced cirrhosis. Methods: Twenty-four male Rats were randomly divided into 6 groups (control, received olive oil, CCL4, Camel Milk treated, Camel urine treated, and Camel urine-Milk treated). The CCL4-induced cirrhosis model in groups 3 to 6, was intraperitoneal injection of CCL4. Rats in control, olive oil, and CCL4 groups, intraperitoneally received CCL4 to induce cirrhosis. In the treatment groups, Camel Milk, urine, and their combination were gavaged respectively. Initial and final body weight as well as serum levels of AST, ALT, ALP, albumin and triglyceride and total cholesterol, were measured in all groups. Liver morphology was assessed using Hematoxellin-Eosin (H&E) staining. Data statistical analysis was carried out using one way ANOVA and Tukey post-hoc (in case of significance) tests. Results: In this study, Serum level of AST, ALT and ALP significantly increased in the CCL4 group compared to the control group, there was no significant difference in the body weight among most groups; but only the simultaneous consumption of Camel’ s Milk and urine in cirrhotic Rats decreased the serum levels of ALT, ALP, and triglyceride compared to the CCL4 group. Conclusion: the findings of the present study indicated that simultaneous consumption of Camel urine and Milk improve cell damage induced by CCL4.

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APA: Copy

ABABZADEH, SHIMA, Sharifi Moghaddam, Soroush, Eftekhari, Seyed Shahin, ESLAMI FARSANI, MOHSEN, Hassanzadeh, Navid, & MOSLEHI, AZAM. (2019). The Effect of Simultaneous Oral Consumption of Camel Milk and Urine on Cirrhosis Liver Model Induced by Carbon Tetrachloride in Male Rats. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 13(3 ), 32-39. SID. https://sid.ir/paper/132023/en

Vancouver: Copy

ABABZADEH SHIMA, Sharifi Moghaddam Soroush, Eftekhari Seyed Shahin, ESLAMI FARSANI MOHSEN, Hassanzadeh Navid, MOSLEHI AZAM. The Effect of Simultaneous Oral Consumption of Camel Milk and Urine on Cirrhosis Liver Model Induced by Carbon Tetrachloride in Male Rats. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2019;13(3 ):32-39. Available from: https://sid.ir/paper/132023/en

IEEE: Copy

SHIMA ABABZADEH, Soroush Sharifi Moghaddam, Seyed Shahin Eftekhari, MOHSEN ESLAMI FARSANI, Navid Hassanzadeh, and AZAM MOSLEHI, “The Effect of Simultaneous Oral Consumption of Camel Milk and Urine on Cirrhosis Liver Model Induced by Carbon Tetrachloride in Male Rats,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 13, no. 3 , pp. 32–39, 2019, [Online]. Available: https://sid.ir/paper/132023/en

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