Association of Dietary Acid Load with Body Composition and Inflammatory Biomarkers in Patients with Type 2 Diabetes

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Kord Varkaneh Hamed; Fatahi Somayeh; Rahmani Jamal; SHAB BIDAR SAKINEH

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Journal: Qom University of Medical Sciences Journal Year:2018 | Volume:12 | Issue:6 Page(s): 63-72

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Information Journal Paper

Title

Association of Dietary Acid Load with Body Composition and Inflammatory Biomarkers in Patients with Type 2 Diabetes

Author(s)

Kord Varkaneh Hamed | Fatahi Somayeh | Rahmani Jamal | SHAB BIDAR SAKINEH | Issue Writer Certificate

Keywords

Dietary acid loadQ1

InflammationQ2

Diabetes mellitus type 2Q2

Body compositionQ2

Abstract

Background and Objectives: Increased Dietary acid load lead to increase in risk of diabetes. The aim of this study was to investigate the association between Dietary acid load with Body composition and inflammatory biomarkers in patients with type 2 diabetes. Methods: In this descriptive cross-sectional study, the study population composed of 185 type 2 diabetic patients (with mean age of 51. 62 years). The food frequency questionnaire (containing 147 food items), was completed to assess dietary intake. Then, acid load indices of potential renal acid load (PRAL) and Net Endogenous Acid Production (NEAP), was calculated for each person. Inflammatory factors (Creactive protein, interleukin-6, and TNF-α ), and anthropometric factors (weight, height, waist circumference, and body fat percentage), were measured. Data were analyzed by linear regression, Pearson, and covariance tests. Results: Among the variables, the total body fat percentage (β =0. 190, p=0. 042) and inflammatory factor TNF-α (β =0. 167, p=0. 031) had a positive and significant correlation with PRAL acid load index. Among tertiles of Dietary acid load, only total body fat and TNF-a, were significantly different among the PRAL tertiles, so that the total body fat percentage and TNF-a inflammatory factor, were higher in 2nd and 3rd tertile, respectively, and this relationship remained significant after adjusting for the confounders (p=0. 038, p=0. 032, respectively). Conclusion: The findings of the present study showed that the PRAL index has a positive correlation with increased body fat and TNF-α .

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References

Diet-dependent acid load and type 2 diabetes: Pooled results from three prospective cohort studies

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APA: Copy

Kord Varkaneh, Hamed, Fatahi, Somayeh, Rahmani, Jamal, & SHAB BIDAR, SAKINEH. (2018). Association of Dietary Acid Load with Body Composition and Inflammatory Biomarkers in Patients with Type 2 Diabetes. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 12(6 ), 63-72. SID. https://sid.ir/paper/132046/en

Vancouver: Copy

Kord Varkaneh Hamed, Fatahi Somayeh, Rahmani Jamal, SHAB BIDAR SAKINEH. Association of Dietary Acid Load with Body Composition and Inflammatory Biomarkers in Patients with Type 2 Diabetes. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2018;12(6 ):63-72. Available from: https://sid.ir/paper/132046/en

IEEE: Copy

Hamed Kord Varkaneh, Somayeh Fatahi, Jamal Rahmani, and SAKINEH SHAB BIDAR, “Association of Dietary Acid Load with Body Composition and Inflammatory Biomarkers in Patients with Type 2 Diabetes,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 12, no. 6 , pp. 63–72, 2018, [Online]. Available: https://sid.ir/paper/132046/en

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