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Information Journal Paper

Title

THE EFFECT OF HIGH-INTENSITY INTERVAL TRAINING AND L-ARGININE SUPPLEMENTATION ON SERUM LEVEL OF IRISIN AND BODY FAT PERCENTAGE IN OVERWEIGHT AND OBESE MEN: A RANDOMIZED CLINICAI TRIAL

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  1-9

Abstract

 Background and Objectives: IRISIN, as a myokine, has been known in reducing obesity and converting white to brown adipose tissue. The purpose of this study was to investigate the effect of high-intensity interval training and L-arginine supplementation on serum level of IRISIN and body fat percentage in overweight and obese men.Methods: In this randomized clinical trial, 40 young healthy overweight and obese men (mean age, 24.5±6.5 years and body mass index, 29.4 ± 3.6kg/m2), were randomly assigned to 4 groups of high-intensity interval training, L-arginine supplementation, high-intensity interval training+L-arginine supplementation, and placebo. The training program consisted of 3 sessions/week high-speed interval running for 6 weeks. L-arginine supplement was consumed orally 6gr/day. Blood sampling and measurement of body fat percentage, was performed 24 hours before and 48 hours after training program and supplementation. Data were analyzed using ANCOVA and post-hoc Bonferroni tests (p<0.05).Results: The serum level of IRISIN significantly increased following 6 weeks of high-intensity interval training and high-intensity interval training+L-arginine supplementation (pvalues=0.017 and 0.019, respectively). While L-arginine consumption did not cause any significant changes in the level of IRISIN (p=0.19). Body fat percentage had no significant changes following 6 weeks of high-intensity training and L-arginine consumption (p>0.05).Conclusion: According to the findings of this study, 6 weeks of high-intensity interval training and high-intensity interval training accompanied by L-arginine supplementation can be an effective step in facilitating the activation of brown adipose tissue through increasing the serum level of IRISIN. Thus, high-intensity interval training can be used as a method in the treatment of obesity.

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    APA: Copy

    CHERAGH BIRJANDI, SADEGH, SAGHEBJOO, MARZIYEH, & HEDAYATI, MEHDI. (2017). THE EFFECT OF HIGH-INTENSITY INTERVAL TRAINING AND L-ARGININE SUPPLEMENTATION ON SERUM LEVEL OF IRISIN AND BODY FAT PERCENTAGE IN OVERWEIGHT AND OBESE MEN: A RANDOMIZED CLINICAI TRIAL. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 11(9 ), 1-9. SID. https://sid.ir/paper/132143/en

    Vancouver: Copy

    CHERAGH BIRJANDI SADEGH, SAGHEBJOO MARZIYEH, HEDAYATI MEHDI. THE EFFECT OF HIGH-INTENSITY INTERVAL TRAINING AND L-ARGININE SUPPLEMENTATION ON SERUM LEVEL OF IRISIN AND BODY FAT PERCENTAGE IN OVERWEIGHT AND OBESE MEN: A RANDOMIZED CLINICAI TRIAL. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2017;11(9 ):1-9. Available from: https://sid.ir/paper/132143/en

    IEEE: Copy

    SADEGH CHERAGH BIRJANDI, MARZIYEH SAGHEBJOO, and MEHDI HEDAYATI, “THE EFFECT OF HIGH-INTENSITY INTERVAL TRAINING AND L-ARGININE SUPPLEMENTATION ON SERUM LEVEL OF IRISIN AND BODY FAT PERCENTAGE IN OVERWEIGHT AND OBESE MEN: A RANDOMIZED CLINICAI TRIAL,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 11, no. 9 , pp. 1–9, 2017, [Online]. Available: https://sid.ir/paper/132143/en

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