THE EFFECT OF OLIGOFRUCTOSE- ENRICHED INULIN ON GLYCEMIC INDICES AND INFLAMMATION IN WOMEN WITH TYPE 2 DIABETES: A RANDOMIZED CLINICAL TRAIL

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DEHGHAN PARVIN; POURGHASSEM GARGARI BAHRAM; SALEK ZAMANI SHABNAM

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Journal: Qom University of Medical Sciences Journal Year:2014 | Volume:8 | Issue:2 Page(s): 34-43

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Title

THE EFFECT OF OLIGOFRUCTOSE- ENRICHED INULIN ON GLYCEMIC INDICES AND INFLAMMATION IN WOMEN WITH TYPE 2 DIABETES: A RANDOMIZED CLINICAL TRAIL

Author(s)

DEHGHAN PARVIN | POURGHASSEM GARGARI BAHRAM | SALEK ZAMANI SHABNAM | Issue Writer Certificate

Keywords

OLIGOFRUCTOSE- ENRICHED INULINQ2

DIABETES MELLITUSQ1

TYPE 2Q3

INSULINQ3

HOMA-IRQ2

INFLAMMATIONQ2

A RANDOMIZED CLINICAL TRAILQ2

Abstract

The Effect of OLIGOFRUCTOSE- ENRICHED INULIN on Glycemic Indices and INFLAMMATION in Women with TYPE 2 Diabetes: A RANDOMIZED CLINICAL TRAIL Background and Objectives: Considering the high prevalence of diabetes and the important role of INSULIN resistance and INFLAMMATION in TYPE 2 diabetes pathogenesis and its resulted cardiovascular diseases, the present study was conducted with the objective of investigating the effect of oligofructose-enriched inulin on the levels of glycemic indices and INFLAMMATION in patients with TYPE 2 diabetes.Methods: In this clinical trial, 52 patients with TYPE 2 diabetes were randomly assigned to two groups. The subjects of experimental group (n=27) received 10g oligofructose-enriched inulin and the control group (n=25) 10g maltodextrin for 8 weeks. Dietary intakes, anthropometric measurements, glycemic indices and INFLAMMATION were measured at the baseline and at the end of the study. Statistical analysis was done using paired and independent t-tests, and analysis of covariance for comparison of quantitative variables.Results: In this study, a significant decrease was observed in fasting blood sugar, HbA1c, IL-6 and TNF-a in OLIGOFRUCTOSE- ENRICHED INULIN group compared to the maltodextrin group. Decreases in HOMA-IR, QUICKI, hs-CRP were not significant in oligofructose-enriched inulin compared to maltodextrin group.Conclusion: The results revealed that oligofructose-enriched inulin supplementation can improve glycemic indices and INFLAMMATION in women with TYPE 2 diabetes.

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APA: Copy

DEHGHAN, PARVIN, POURGHASSEM GARGARI, BAHRAM, & SALEK ZAMANI, SHABNAM. (2014). THE EFFECT OF OLIGOFRUCTOSE- ENRICHED INULIN ON GLYCEMIC INDICES AND INFLAMMATION IN WOMEN WITH TYPE 2 DIABETES: A RANDOMIZED CLINICAL TRAIL. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 8(2), 34-43. SID. https://sid.ir/paper/132158/en

Vancouver: Copy

DEHGHAN PARVIN, POURGHASSEM GARGARI BAHRAM, SALEK ZAMANI SHABNAM. THE EFFECT OF OLIGOFRUCTOSE- ENRICHED INULIN ON GLYCEMIC INDICES AND INFLAMMATION IN WOMEN WITH TYPE 2 DIABETES: A RANDOMIZED CLINICAL TRAIL. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2014;8(2):34-43. Available from: https://sid.ir/paper/132158/en

IEEE: Copy

PARVIN DEHGHAN, BAHRAM POURGHASSEM GARGARI, and SHABNAM SALEK ZAMANI, “THE EFFECT OF OLIGOFRUCTOSE- ENRICHED INULIN ON GLYCEMIC INDICES AND INFLAMMATION IN WOMEN WITH TYPE 2 DIABETES: A RANDOMIZED CLINICAL TRAIL,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 8, no. 2, pp. 34–43, 2014, [Online]. Available: https://sid.ir/paper/132158/en

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