The Effect of Cyclic Lipopeptides of Bacillus atrophaeus (HNSQJYH170) on Candida Species

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Moghtadi Pisheh Seyedeh Solmaz; MADANI MAHBOOBEH

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Journal: QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL Year:2018 | Volume:12 | Issue:3 Page(s): 19-27

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Title

The Effect of Cyclic Lipopeptides of Bacillus atrophaeus (HNSQJYH170) on Candida Species

Author(s)

Moghtadi Pisheh Seyedeh Solmaz | MADANI MAHBOOBEH | Issue Writer Certificate

Keywords

Bacillus atrophaeusQ1

LipopeptideQ1

germ tubeQ1

CandidaQ1

Abstract

Background and Objectives: Over the past years, several factors, such as broad spectrum of antibiotics, immunodeficiency, chemotherapy, and transplantation have increased the risk of fungal infections in human. Among the fungal pathogens, Candida species are the most common cause of invasive fungal infections. The aim of this study was to investigate the antifungal effect of Bacillus atrophaeus (HNSQJYH170) Lipopeptides on Candida species. Methods: In this experimental study, Bacillus atrophaeus (HNSQJYH170) isolated from Isfahan soil, was cultured in nutrient broth medium. Cell-free supernatant was collected by centrifugation and acidified by adding HCl. The obtained precipitate was collected by centrifugation and dissolved in the methanol solution 50%. Then, antifungal activity of Lipopeptides against Candida species, was assessed by well diffusion method. Also, inhibitory effect of Lipopeptide on germ tube production, was studied for Candida albicans. Results: Results showed that Bacillus atrophaeus (HNSQJYH170) Lipopeptides do not have inhibitory effect on germ tube production in %95 of Candida albicans cells. Conclusion: According to the results of this research, probably Bacillus atrophaeus (HNSQJYH170) can inhibit Candida albicans invasion. Therefore, further researches are needed to confirm the results of this study.

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References

ISOLATION AND IDENTIFICATION OF INHIBITORY BACTERIA AGAINST PATHOGENIC FUNGI FROM ISFAHAN USING MOLECULAR METHOD

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APA: Copy

Moghtadi Pisheh, Seyedeh Solmaz, & MADANI, MAHBOOBEH. (2018). The Effect of Cyclic Lipopeptides of Bacillus atrophaeus (HNSQJYH170) on Candida Species. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, 12(3 ), 19-27. SID. https://sid.ir/paper/132280/en

Vancouver: Copy

Moghtadi Pisheh Seyedeh Solmaz, MADANI MAHBOOBEH. The Effect of Cyclic Lipopeptides of Bacillus atrophaeus (HNSQJYH170) on Candida Species. QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL[Internet]. 2018;12(3 ):19-27. Available from: https://sid.ir/paper/132280/en

IEEE: Copy

Seyedeh Solmaz Moghtadi Pisheh, and MAHBOOBEH MADANI, “The Effect of Cyclic Lipopeptides of Bacillus atrophaeus (HNSQJYH170) on Candida Species,” QOM UNIVERSITY OF MEDICAL SCIENCES JOURNAL, vol. 12, no. 3 , pp. 19–27, 2018, [Online]. Available: https://sid.ir/paper/132280/en

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