مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

An Overview of Statistical and Clinical Concepts: The Use and Interpretation of Confidence Interval

Pages

  696-707

Abstract

 Application and interpretation of statistical significance of association are the basic and necessary principle in medical research. Traditionally, hypothesis testing and reporting p-values have been extensively utilized to quantify the statistical significance of observed results. The majority of published research that involves statistical inference seems to make exclusive use of hypothesis testing, and summarize their findings only to statistical significance. Most importantly, p-value fail to provide two crucial pieces of information: (1) the magnitude of an effect of interest, and (2) the precision of the estimate of the magnitude of that effect. Currently, most of the reputable journals no longer accept statistical significance alone; and there has been increasing attention focused on the Effect size index, confidence limits along with clinical significant. However, there is no single guideline for reporting statistical and clinical significance, and there are inconsistencies between journals. The aim of this paper is to provide a correct and integrated instruction for reporting statistical and clinical significance in medical sciences employing an estimation approach (reporting confidence interval).

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