Non-coding RNAs as non-invasive diagnostic biomarkers for lung cancer

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Tahernejad Mina; Hamidiazar Sara; Jamshidian Faranak

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Journal Paper

Paper Information

Journal: JOURNAL OF HUMAN GENETICS AND GENOMICS Year:2023 | Volume:7 | Issue:2 Page(s): 1-8

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Information Journal Paper

Title

Non-coding RNAs as non-invasive diagnostic biomarkers for lung cancer

Author(s)

Tahernejad Mina | Hamidiazar Sara | Jamshidian Faranak | Issue Writer Certificate

Keywords

Lung neoplasmQ4

ncRNAsQ4

lncRNAQ4

miRNAQ4

circRNAQ4

ExosomesQ4

Diagnosis diagnosisQ4

Abstract

Lung cancer stands as the second most prevalent cause of cancer-related mortality worldwide and is mainly influenced by delayed diagnosis, even with available therapeutic alternatives. The most recent studies indicate that non-coding RNAs (ncRNAs) are involved with maintaining homeostasis in cells, particularly in gene expression regulation. Hence dysregulation of these ncRNAs may develop cancer. ncRNAs in biofluids like blood, urine, saliva, serum, and plasma Exosomes provide a non-invasive and less painful approach to detecting lung cancer progression. In this review novel studies for subclasses of ncRNAs such as long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and circular RNAs (circRNA) have been summarized to determine the most Potential biomarkers for prognose lung cancer.

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