Medicinal Plants for Treatment Tauopathy-Recent Advances in Targeting Tau Phosphorylation

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Mohammad Soheil Maveddat; Banafshe Salehi; Bahareh Salehi; Jamali Behdokht; Koorosh Shahpasand

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF HUMAN GENETICS AND GENOMICS Year:2023 | Volume:7 | Issue:2 Page(s): 1-7

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Title

Medicinal Plants for Treatment Tauopathy-Recent Advances in Targeting Tau Phosphorylation

Author(s)

Keywords

TauQ4

HyperphosphorylationQ4

TauopathyQ4

Alzheimer's diseaseQ4

Medicinal plant.Q4

Abstract

The prevalence of neurodegenerative diseases such as Alzheimer's disease (AD) has increased in recent years and put additional strain on the health systems of most countries. Although great progress has been made in the treatment of these diseases, so far no effective treatment has been found that can block the progression of these diseases. In recent years, there have been reports of inhibition of Hyperphosphorylation of Tau protein by extracts or natural compounds derived from Medicinal plant.. In this review article, we tried to review some of the Medicinal plant. that have shown these effects in electronic databases. Some Medicinal plant. including Curcuma longa, Rosmarinus officinalis, Vitis vinifera, Apocynum venetum, Centella asiatica, Rhus succedanea, Maclura pomifera Allium sativum and Ginkgo biloba have been found to show anti-Tau Hyperphosphorylation effects and therefore can be considered as adjuvant therapy in Alzheimer disease (AD). The essential oils or natural product of some Medicinal plant.inhibited the Tau Hyperphosphorylation in studies and as results are suitable options in treatments of neurodegenerative diseases including AD.

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