wSurface plasmon resonance optical fiber sensor to detect glucose concentration in human blood

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Afroozeh Abdolkarim

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Journal Paper

Paper Information

Journal: ADVANCES IN SKIN, WOUND AND TISSUE REPAIR Year:2024 | Volume:21 | Issue:2 Page(s): 9-19

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Information Journal Paper

Title

wSurface plasmon resonance optical fiber sensor to detect glucose concentration in human blood

Author(s)

Afroozeh Abdolkarim | Issue Writer Certificate

Keywords

Sensor

optical fiber

surface plasmon resonance

temperature compensation.

Abstract

wFiber optic sensor based on surface plasmon resonance has certain drawbacks, including limitations in linearity and vulnerability to external temperature fluctuations. In order to achieve this goal, we evaluate a temperature-compensated surface plasmon resonance biosensor that uses a Mach-Zehnder interferometer. The biosensor is made with a structure consisting of a tapered multimode fiber, a single mode fiber and another multimode fiber. The surface plasmon resonance phenomenon is caused by a silver layer modified using reduced graphene oxide and pyrene-boric acid, which brings glucoses together through π-π interactions and glucose bonding. creates Compensation of the effect of ambient temperature on surface plasmon resonance is obtained by stimulating the effect of Mach-Zehnder interferometer using the structure of a single-mode fiber and a multi-mode fiber. In order to investigate the signals of Mach-Zehnder interferometer and surface plasmon resonance separately, we used fast Fourier transform to distinguish the effects of Mach-Zehnder interferometer and surface plasmon resonance. The linearity of the sensor was improved by using a center fitting method that uses the shift of the center coordinates calculated from a single resonant surface plasmon gradient instead of the resonance wavelength. Our test results showed that our sensor has a glucose sensitivity of 2.819 nM/mM. It has a linear range of 0 to 10 mmol/L and is capable of simultaneous temperature compensation. The surface plasmon resonance sensor proposed in this research is compactly designed and suitable for accurate detection of glucose concentration in human blood.

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