THE EFFECT OF SALVIA LERIIFOLIA BENTH. ROOT EXTRACTS ON LIPID PEROXIDATION LEVEL DURING GLOBAL ISCHEMIC - REPERFUSION IN RATS.

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SADEGHNIA H.R.; NASIRIASL M.; HADAD KHODAPARAST MOHAMMAD HOSSEIN; HOSSEINZADEH H.

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Journal: Journal of Medicinal Plants Year:2003 | Volume:2 | Issue:7 Page(s): 19-28

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Information Journal Paper

Title

THE EFFECT OF SALVIA LERIIFOLIA BENTH. ROOT EXTRACTS ON LIPID PEROXIDATION LEVEL DURING GLOBAL ISCHEMIC - REPERFUSION IN RATS.

Author(s)

SADEGHNIA H.R. | NASIRIASL M. | HADAD KHODAPARAST MOHAMMAD HOSSEIN | HOSSEINZADEH H. | Issue Writer Certificate

Keywords

SALVIA LERIIFOLIA ROOTQ4

FREE RADICALQ4

FOUR - VESSEL - OCCLUSIONQ4

LIPID PEROXIDATIONQ4

MALONDIALDEHYDE.Q4

Abstract

The previous pathological data has revealed that SALVIA LERIIFOLIA ROOT extracts have a neuroprotective activity against cerebral ischemia, thus the effect of the root extracts on LIPID PEROXIDATION was evaluated using experimental global ischemic - occlusion (4VO) for 20 min. the aqueous and ethanolic extracts (0.1 , 0.2 and 0.4 g/kg), phenytoin, as positive control, (50 mg/kg) and normal saline (10 ml/kg) were administered intraperitoneally 15 min after the induction of ischemia. The MALONDIALDEHYDE.(MDA) was measured by the thiobarbituric acid (TBA) test. The MDA level was higher in the saline group than the sham group. The MDA levels were recovered significantly upon phenytoin and the extracts therapy in the hippocampus of ischemic rats. These results suggest that S. leriifolia root extracts may show a protective effect against LIPID PEROXIDATION in cerebral ischemia.

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APA: Copy

SADEGHNIA, H.R., NASIRIASL, M., HADAD KHODAPARAST, MOHAMMAD HOSSEIN, & HOSSEINZADEH, H.. (2003). THE EFFECT OF SALVIA LERIIFOLIA BENTH. ROOT EXTRACTS ON LIPID PEROXIDATION LEVEL DURING GLOBAL ISCHEMIC - REPERFUSION IN RATS.. JOURNAL OF MEDICINAL PLANTS, 2(7), 19-28. SID. https://sid.ir/paper/15565/en

Vancouver: Copy

SADEGHNIA H.R., NASIRIASL M., HADAD KHODAPARAST MOHAMMAD HOSSEIN, HOSSEINZADEH H.. THE EFFECT OF SALVIA LERIIFOLIA BENTH. ROOT EXTRACTS ON LIPID PEROXIDATION LEVEL DURING GLOBAL ISCHEMIC - REPERFUSION IN RATS.. JOURNAL OF MEDICINAL PLANTS[Internet]. 2003;2(7):19-28. Available from: https://sid.ir/paper/15565/en

IEEE: Copy

H.R. SADEGHNIA, M. NASIRIASL, MOHAMMAD HOSSEIN HADAD KHODAPARAST, and H. HOSSEINZADEH, “THE EFFECT OF SALVIA LERIIFOLIA BENTH. ROOT EXTRACTS ON LIPID PEROXIDATION LEVEL DURING GLOBAL ISCHEMIC - REPERFUSION IN RATS.,” JOURNAL OF MEDICINAL PLANTS, vol. 2, no. 7, pp. 19–28, 2003, [Online]. Available: https://sid.ir/paper/15565/en

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