PATHOLOGIC EVALUATION OF ANTI-ISCHEMIC EFFECT OF SALVIA LERIIFOLIA BENTH SEED AND LEAF EXTRACTS IN RATS AFTER GLOBAL CEREBRAL ISCHEMIA

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KHOUEI A.R.; HOSSEINZADEH H.; IMEN SHAHIDI M.

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Journal: Iranian Journal of Basic Medical Sciences Year:2003 | Volume:5 | Issue:4 (16) Page(s): 8-13

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Title

PATHOLOGIC EVALUATION OF ANTI-ISCHEMIC EFFECT OF SALVIA LERIIFOLIA BENTH SEED AND LEAF EXTRACTS IN RATS AFTER GLOBAL CEREBRAL ISCHEMIA

Author(s)

KHOUEI A.R. | HOSSEINZADEH H. | IMEN SHAHIDI M. | Issue Writer Certificate

Keywords

ANTI-ISCHEMIC ACTIVITYQ4

HIPPOCAMPUSQ4

SALVIA LERIIFOLIAQ2

SEEDQ4

LEAFQ4

Abstract

The anti-ischemic effect of SALVIA LERIIFOLIA SEED and LEAF aqueous extracts was studied in rats. Ischemia was induced using four-vessel occlusion method and evaluated by optical microscope, in rat. Phytochemical screening of the extracts showed that both extracts comprised tannins, the LEAF extract contained saponins as well. In ischemic rats, the aqueous LEAF extract could not reduced ischemic damage but the aqueous SEED extract (2.4 g/kg, i.p.) significantly reduced neural cell injury in the hippocampal neurons. Phenytoin (50 mg/kg, i.p.), as a positive control, also exerted an anti-ischemic effect. These results indicate that S. leriifolia SEED extract has a protective effect against ischemia.

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APA: Copy

KHOUEI, A.R., HOSSEINZADEH, H., & IMEN SHAHIDI, M.. (2003). PATHOLOGIC EVALUATION OF ANTI-ISCHEMIC EFFECT OF SALVIA LERIIFOLIA BENTH SEED AND LEAF EXTRACTS IN RATS AFTER GLOBAL CEREBRAL ISCHEMIA. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 5(4 (16)), 8-13. SID. https://sid.ir/paper/378803/en

Vancouver: Copy

KHOUEI A.R., HOSSEINZADEH H., IMEN SHAHIDI M.. PATHOLOGIC EVALUATION OF ANTI-ISCHEMIC EFFECT OF SALVIA LERIIFOLIA BENTH SEED AND LEAF EXTRACTS IN RATS AFTER GLOBAL CEREBRAL ISCHEMIA. IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES[Internet]. 2003;5(4 (16)):8-13. Available from: https://sid.ir/paper/378803/en

IEEE: Copy

A.R. KHOUEI, H. HOSSEINZADEH, and M. IMEN SHAHIDI, “PATHOLOGIC EVALUATION OF ANTI-ISCHEMIC EFFECT OF SALVIA LERIIFOLIA BENTH SEED AND LEAF EXTRACTS IN RATS AFTER GLOBAL CEREBRAL ISCHEMIA,” IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, vol. 5, no. 4 (16), pp. 8–13, 2003, [Online]. Available: https://sid.ir/paper/378803/en

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