CUTANEOUS REACTIONS OF ANTICONVULSANT DRUGS

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MALEKAFZALI BAHAREH; NAJIBI FRANAK

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

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Journal: Dermatology and Cosmetics Year:2011 | Volume:2 | Issue:1 Page(s): 30-34

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Title

CUTANEOUS REACTIONS OF ANTICONVULSANT DRUGS

Author(s)

MALEKAFZALI BAHAREH | NAJIBI FRANAK | Issue Writer Certificate

Keywords

CUTANEOUS REACTIONQ3

DRUG ERUPTIONQ2

ANTICONVULSANTQ3

SIDE EFFECTQ3

Abstract

Background and Aim: Cutaneous drug reaction is a common SIDE EFFECT of antiepileptic drugs and a frequent cause of treatment discontinuation. These reactions ranges can be a mild maculopapular rash to Stevens-Johnson Syndrom and toxic epidermal necrolysis. Among the traditional ANTICONVULSANT drugs the aromatic compounds Phenytoin, Phenobarbital and Carbamazepin have been associated with relatively higher incidences of CUTANEOUS REACTIONs which can hospitalized the patient. Some of the newer drugs also can induce this problem, especially lamotrigine.Methods: All records of patiens who were hospitalized at hospitals related to Islamic Azad as well as Rasol Akram hospital with a diagnosis of cutaneous drug reaction to ANTICONVULSANT therapy in 8 years period were reviewed.Results: The most common culprit was phenytoin (32%) and the least common drug was lamotrigin (3%).Conclusion: CUTANEOUS REACTION to ANTICONVULSANT drugs is common and sometimes may be life threatening which needs serious treatment options.

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APA: Copy

MALEKAFZALI, BAHAREH, & NAJIBI, FRANAK. (2011). CUTANEOUS REACTIONS OF ANTICONVULSANT DRUGS. DERMATOLOGY AND COSMETIC, 2(1), 30-34. SID. https://sid.ir/paper/157555/en

Vancouver: Copy

MALEKAFZALI BAHAREH, NAJIBI FRANAK. CUTANEOUS REACTIONS OF ANTICONVULSANT DRUGS. DERMATOLOGY AND COSMETIC[Internet]. 2011;2(1):30-34. Available from: https://sid.ir/paper/157555/en

IEEE: Copy

BAHAREH MALEKAFZALI, and FRANAK NAJIBI, “CUTANEOUS REACTIONS OF ANTICONVULSANT DRUGS,” DERMATOLOGY AND COSMETIC, vol. 2, no. 1, pp. 30–34, 2011, [Online]. Available: https://sid.ir/paper/157555/en

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