CUTANEOUS AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH BETA MAJOR THALASSEMIA

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NADERI MAJID; SHAMSHIRI HAMI; ALIZADEH SHABAN; DORGALALEH AKBAR; MANAFI RIMA; TABIBIAN SHADI

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Journal: Dermatology and Cosmetics Year:2013 | Volume:4 | Issue:1 Page(s): 27-33

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Title

CUTANEOUS AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH BETA MAJOR THALASSEMIA

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Keywords

THALASSEMIAQ3

CUTANEOUS MANIFESTATIONSQ3

MUCOSAL MANIFESTATIONSQ2

DERMATOLOGYQ3

Abstract

Background and Aim: THALASSEMIA is one of the most common single gene disorder that results from decrease or absence of globulin chain(s) synthesis. Repeated blood transfusion is required for prevention of severe anemia and related side effects, but it is associated with other complications such as cutaneous lesions and MUCOSAL MANIFESTATIONS. This study conducted to assess the frequency of cutaneous and MUCOSAL MANIFESTATIONS in patients with beta THALASSEMIA.Methods: This cross-sectional study was conducted on 300 patients with beta major THALASSEMIA in Zahedan. Data were obtained from medical records and questionnaires as well as through physical examination of patients. The data were statistically described and tested.Results: The mean age of patients was 17.9±6.3 years and 64.3% of patients were men and 35.7% were women. Among cutaneous lesions, freckles were the most common (70.7%) and the rarest one was peri orbital pigmentation (0.3%). Gingivitis (41.7%) and longitudinal lines on nails (72%) were the most common mucosal and nail manifestations.Conclusion: Since cutaneous and MUCOSAL MANIFESTATIONS are very common among patients with beta major THALASSEMIA, regular DERMATOLOGY follow up of these patients is recommended.

Cites

THE REPRODUCTIVE BEHAVIOR OF FAMILIES WITH THALASSEMIC CHILDREN IN HORMOZGAN (SHORT COMMUNICATION)

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APA: Copy

NADERI, MAJID, SHAMSHIRI, HAMI, ALIZADEH, SHABAN, DORGALALEH, AKBAR, MANAFI, RIMA, & TABIBIAN, SHADI. (2013). CUTANEOUS AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH BETA MAJOR THALASSEMIA. DERMATOLOGY AND COSMETIC, 4(1), 27-33. SID. https://sid.ir/paper/157660/en

Vancouver: Copy

NADERI MAJID, SHAMSHIRI HAMI, ALIZADEH SHABAN, DORGALALEH AKBAR, MANAFI RIMA, TABIBIAN SHADI. CUTANEOUS AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH BETA MAJOR THALASSEMIA. DERMATOLOGY AND COSMETIC[Internet]. 2013;4(1):27-33. Available from: https://sid.ir/paper/157660/en

IEEE: Copy

MAJID NADERI, HAMI SHAMSHIRI, SHABAN ALIZADEH, AKBAR DORGALALEH, RIMA MANAFI, and SHADI TABIBIAN, “CUTANEOUS AND MUCOSAL MANIFESTATIONS IN PATIENTS WITH BETA MAJOR THALASSEMIA,” DERMATOLOGY AND COSMETIC, vol. 4, no. 1, pp. 27–33, 2013, [Online]. Available: https://sid.ir/paper/157660/en

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