A COOPERATIVE GAME MODEL FOR MICROARRAY DATA PROCESSING

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KORDVANDI Y.; NAVIDI H.R.; HASSAN POUR EZATI M.

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Journal: Journal of Operational Research in its Applications Year:2014 | Volume:10 | Issue:4 (39) Page(s): 69-83

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Information Journal Paper

Title

A COOPERATIVE GAME MODEL FOR MICROARRAY DATA PROCESSING

Author(s)

KORDVANDI Y. | NAVIDI H.R. | HASSAN POUR EZATI M. | Issue Writer Certificate

Keywords

COOPERATIVE GAME THEORYQ2

MICROARRAY GAMEQ2

COMPARATIVE ANALYSIS OF SHAPLEY VALUEQ2

GENE EXPRESSIONQ2

Abstract

A microarray is a small analytical device that allows genomic analysis with speed and precision. Through this technology the expression of thousands of genes can be simultaneously explored. Fundamental question about the microarray data is how to choose the genetic markers. Detection of genetic markers, shall lead to early detection, treatment, and accurately prognosis; therefore, appropriate treatment and reduction of cost. Using a classical approach for microarray data processing and statistical analysis, we are able to detect only two genes as differentially regulated in samples under investigation. Recently, in an effort to boost the biologically meaningful signal, game theory researchers, have been able to devise a method on GENE EXPRESSION data, Thus we were able to identify a group of genes associated with a disorder. This method, which is called COMPARATIVE ANALYSIS OF SHAPLEY VALUE, by combining the concept of Shapley value of cooperative games and statistical bootstrap lead to selection of genes with powerful influence in occurrence of a disorder. In this paper, this approach will be developed and in a case study of this modeling the results of applying this approach on GENE EXPRESSION data from autistic individuals, showed that coalitional games significantly increase the power to identify candidates.

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APA: Copy

KORDVANDI, Y., NAVIDI, H.R., & HASSAN POUR EZATI, M.. (2014). A COOPERATIVE GAME MODEL FOR MICROARRAY DATA PROCESSING. JOURNAL OF OPERATIONAL RESEARCH AND ITS APPLICATIONS (JOURNAL OF APPLIED MATHEMATICS), 10(4 (39)), 69-83. SID. https://sid.ir/paper/164643/en

Vancouver: Copy

KORDVANDI Y., NAVIDI H.R., HASSAN POUR EZATI M.. A COOPERATIVE GAME MODEL FOR MICROARRAY DATA PROCESSING. JOURNAL OF OPERATIONAL RESEARCH AND ITS APPLICATIONS (JOURNAL OF APPLIED MATHEMATICS)[Internet]. 2014;10(4 (39)):69-83. Available from: https://sid.ir/paper/164643/en

IEEE: Copy

Y. KORDVANDI, H.R. NAVIDI, and M. HASSAN POUR EZATI, “A COOPERATIVE GAME MODEL FOR MICROARRAY DATA PROCESSING,” JOURNAL OF OPERATIONAL RESEARCH AND ITS APPLICATIONS (JOURNAL OF APPLIED MATHEMATICS), vol. 10, no. 4 (39), pp. 69–83, 2014, [Online]. Available: https://sid.ir/paper/164643/en

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