RELATIONSHIP OF SCHIZOPHRENIA WITH LIPID PEROXIDATION, TOTAL SERUM ANTIOXIDANT CAPACITY AND THIOL GROUPS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SALEHI BAHMAN; VAKILIAN K.; RANJBAR AKRAM

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Psychiatry and Clinical Psychology Year:2008 | Volume:14 | Issue:2 (53) Page(s): 140-145

Download Full-Text

Persian Verion

View:

1,236

Download:

Cites:

Information Journal Paper

Title

RELATIONSHIP OF SCHIZOPHRENIA WITH LIPID PEROXIDATION, TOTAL SERUM ANTIOXIDANT CAPACITY AND THIOL GROUPS

Author(s)

SALEHI BAHMAN | VAKILIAN K. | RANJBAR AKRAM | Issue Writer Certificate

Keywords

SCHIZOPHRENIAQ3

THIOLQ3

LIPID PEROXIDATIONQ3

TOTAL ANTIOXIDANT CAPACITYQ3

Abstract

Objectives: Considering the important effects of increase in free radicals such as superoxidase and nitric oxide on deficiency in antioxidant defense and the harm done to brain, this research was carried out with the aim of comparing oxidative stress in patients with SCHIZOPHRENIA and normal individuals.Method: This cross-sectional study was carried out on 60 patients who were diagnosed with SCHIZOPHRENIA based on Diagnostic and Statistical Manual of Mental Disorders-fourth edition-Text Revision (DSM-IV-TR) criteria by a psychiatrist, and 180 normal subjects who were matched based on age, sex, smoking and income. Patients were selected using convenience sampling in Amir Kabir Hospital. After filling consent forms, five ml of venous blood sample was drawn from the subjects for measuring stress oxidative indexes. Satho and thiobarbitoric acid (TBA) methods were used to measure LIPID PEROXIDATION, Hu and Dithionitrobenzoic acid (DTNB) were used to measure THIOL groups, and Ferric Reducing Ability of Plasma (FRAP) which evaluates plasma ability in ferric ion reduction was used to measure total serum antioxidative activity. Data were analyzed using Spearman correlation coefficient, t-test, and logistic regression pattern.Results: The mean age of subjects was 32.13 (±9.46). Seven and 53 patients had acute and chronic SCHIZOPHRENIA respectively. The mean difference of THIOL index between the subject and control groups was significant (p<0.001). Mean of FRAP index was also significantly different between the two groups (p<0.005). The mean for TBA index was higher in the subject group but the difference was not significant.Conclusion: A decrease in THIOL and FRAP leads to a decrease in antioxidant defense in patients with SCHIZOPHRENIA.

Cites

No record.

References

No record.

Cite

APA: Copy

SALEHI, BAHMAN, VAKILIAN, K., & RANJBAR, AKRAM. (2008). RELATIONSHIP OF SCHIZOPHRENIA WITH LIPID PEROXIDATION, TOTAL SERUM ANTIOXIDANT CAPACITY AND THIOL GROUPS. IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY, 14(2 (53)), 140-145. SID. https://sid.ir/paper/16648/en

Vancouver: Copy

SALEHI BAHMAN, VAKILIAN K., RANJBAR AKRAM. RELATIONSHIP OF SCHIZOPHRENIA WITH LIPID PEROXIDATION, TOTAL SERUM ANTIOXIDANT CAPACITY AND THIOL GROUPS. IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY[Internet]. 2008;14(2 (53)):140-145. Available from: https://sid.ir/paper/16648/en

IEEE: Copy

BAHMAN SALEHI, K. VAKILIAN, and AKRAM RANJBAR, “RELATIONSHIP OF SCHIZOPHRENIA WITH LIPID PEROXIDATION, TOTAL SERUM ANTIOXIDANT CAPACITY AND THIOL GROUPS,” IRANIAN JOURNAL OF PSYCHIATRY AND CLINICAL PSYCHOLOGY, vol. 14, no. 2 (53), pp. 140–145, 2008, [Online]. Available: https://sid.ir/paper/16648/en

Related Journal Papers