EFFECT OF SERUM TESTOSTERONE AND DIHYDROTESTOSTERONE LEVELS IN PATIENTS WITH SEBORRHEA

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ESHGHI GHOLAMREZA; LOHRASBI FARZAD; SOLTANIAN ALIREZA; REZANEJAD ALIASGHAR; ALIREZAEI PEDRAM; KHEZRIAN LEYLA

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Journal: Avicenna Journal of Clinical Medicine Year:2016 | Volume:23 | Issue:3 (SN 81) Page(s): 259-265

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Title

EFFECT OF SERUM TESTOSTERONE AND DIHYDROTESTOSTERONE LEVELS IN PATIENTS WITH SEBORRHEA

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Keywords

SEBORRHEAQ1

TESTOSTERONEQ2

DIHYDROTESTOSTERONEQ1

ANDROGENQ1

Abstract

Introduction: SEBORRHEA is a condition of sebaceous glands hyperactivity and increase in the secretion of sebum on head and face surface. Sebaceous glands hyperfunction causes oily and glassy appearance with large pores on the skin. The effect of ANDROGENs on providing SEBORRHEA is controversial. Since sufficient and definite information about TESTOSTERONE and DIHYDROTESTOSTERONE in seborrhic cases is not available, this study was carried out to evaluate effect of serum TESTOSTERONE and DIHYDROTESTOSTERONE levels in the seborrheic patients.Methods: In this case- control study, 36 patients with SEBORRHEA and 36 control individuals, under 40 years of age were selected. Serum TESTOSTERONE and DIHYDROTESTOSTERONE levels were measured in ng/mL. Data were analyzed using SPSS v.16, Chi- square and t- tests (α=0.05).Results: Twenty- three males and 49 females, who referred to the dermatology department of Farshchian Hospital of Hamadan, participated in this study. The age distribution of the participants was between 19 and 39 years old with mean age of 5.71±28.66. The mean level and SD of serum TESTOSTERONE in control and case groups was 2.75±2.83 and±1.21 1.09, respectively, while DIHYDROTESTOSTERONE level was 373±500.38 and 228.2±350.99 ng/mL. Means and SDs values of serum TESTOSTERONE were 2.75±2.83 and 1.09±1.21 and DIHYDROTESTOSTERONE was 373±500.38 and 228.2±350.99 ng/mL in case and control groups, respectively. The findings showed that there were differences in serum TESTOSTERONE and DIHYDROTESTOSTERONE values between case and control groups (P<0.05).Conclusions: According to the results of this study there is a positive relationship between serum TESTOSTERONE and DIHYDROTESTOSTERONE values with SEBORRHEA.

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APA: Copy

ESHGHI, GHOLAMREZA, LOHRASBI, FARZAD, SOLTANIAN, ALIREZA, REZANEJAD, ALIASGHAR, ALIREZAEI, PEDRAM, & KHEZRIAN, LEYLA. (2016). EFFECT OF SERUM TESTOSTERONE AND DIHYDROTESTOSTERONE LEVELS IN PATIENTS WITH SEBORRHEA. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 23(3 (SN 81)), 259-265. SID. https://sid.ir/paper/17439/en

Vancouver: Copy

ESHGHI GHOLAMREZA, LOHRASBI FARZAD, SOLTANIAN ALIREZA, REZANEJAD ALIASGHAR, ALIREZAEI PEDRAM, KHEZRIAN LEYLA. EFFECT OF SERUM TESTOSTERONE AND DIHYDROTESTOSTERONE LEVELS IN PATIENTS WITH SEBORRHEA. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2016;23(3 (SN 81)):259-265. Available from: https://sid.ir/paper/17439/en

IEEE: Copy

GHOLAMREZA ESHGHI, FARZAD LOHRASBI, ALIREZA SOLTANIAN, ALIASGHAR REZANEJAD, PEDRAM ALIREZAEI, and LEYLA KHEZRIAN, “EFFECT OF SERUM TESTOSTERONE AND DIHYDROTESTOSTERONE LEVELS IN PATIENTS WITH SEBORRHEA,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 23, no. 3 (SN 81), pp. 259–265, 2016, [Online]. Available: https://sid.ir/paper/17439/en

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